A congenital case of circumscribed acral hypokeratosis

Joshua Arbesman, Lesley C. Loss, Klaus F. Helm, Ilene L. Rothman

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

Circumscribed acral hypokeratosis is a disorder characterized by areas of erythematous depressed skin with distinct histopathological findings typically found on the palmar and plantar surfaces. Most patients are middle-aged women who report a multiyear history. We present an 10-year-old African American boy who had an asymptomatic, irregularly shaped erythematous lesion on his left medial foot that had been present since birth. A biopsy showed an abrupt, well-demarcated decrease in the thickness of the stratum corneum layer, with no parakeratosis, that was consistent with a diagnosis of circumscribed hypokeratosis. This represents the first pediatric and congenital case of circumscribed hypokeratosis reported. We review the literature and discuss the ramifications of a congenital case on understanding the etiology of circumscribed hypokeratosis.

Original languageEnglish (US)
Pages (from-to)485-487
Number of pages3
JournalPediatric dermatology
Volume29
Issue number4
DOIs
StatePublished - Jul 1 2012

Fingerprint

Parakeratosis
African Americans
Cornea
Foot
Extremities
History
Parturition
Pediatrics
Biopsy
Skin

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

Cite this

Arbesman, Joshua ; Loss, Lesley C. ; Helm, Klaus F. ; Rothman, Ilene L. / A congenital case of circumscribed acral hypokeratosis. In: Pediatric dermatology. 2012 ; Vol. 29, No. 4. pp. 485-487.
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A congenital case of circumscribed acral hypokeratosis. / Arbesman, Joshua; Loss, Lesley C.; Helm, Klaus F.; Rothman, Ilene L.

In: Pediatric dermatology, Vol. 29, No. 4, 01.07.2012, p. 485-487.

Research output: Contribution to journalReview article

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AU - Arbesman, Joshua

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AU - Helm, Klaus F.

AU - Rothman, Ilene L.

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