A congenital case of circumscribed acral hypokeratosis

Joshua Arbesman, Lesley C. Loss, Klaus F. Helm, Ilene L. Rothman

Research output: Contribution to journalReview article

11 Scopus citations

Abstract

Circumscribed acral hypokeratosis is a disorder characterized by areas of erythematous depressed skin with distinct histopathological findings typically found on the palmar and plantar surfaces. Most patients are middle-aged women who report a multiyear history. We present an 10-year-old African American boy who had an asymptomatic, irregularly shaped erythematous lesion on his left medial foot that had been present since birth. A biopsy showed an abrupt, well-demarcated decrease in the thickness of the stratum corneum layer, with no parakeratosis, that was consistent with a diagnosis of circumscribed hypokeratosis. This represents the first pediatric and congenital case of circumscribed hypokeratosis reported. We review the literature and discuss the ramifications of a congenital case on understanding the etiology of circumscribed hypokeratosis.

Original languageEnglish (US)
Pages (from-to)485-487
Number of pages3
JournalPediatric dermatology
Volume29
Issue number4
DOIs
StatePublished - Jul 1 2012

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

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