A Continuing Controversy: Magnesium Sulfate in the Treatment of Eclamptic Seizures

Peter W. Kaplan, Ronald P. Lesser, Robert S. Fisher, John Repke, Daniel F. Hanley

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


We would like to address some of the issues raised by Pritchard1 and Lindheimer2 in their letters to the editor. Pritchard outlines a plan of treatment for eclampsia that includes parenteral magnesium sulfate, intravenous hydralazine, and the delivery of the baby; he is concerned that a proposal for a different treatment regimen for eclampsia would not be approved by a human subjects committee given the apparently satisfactory results of his treatment protocol. In his experience, magnesium sulfate “almost always stops convulsions promptly and prevents their recurrence,” and he comments on the effect of magnesium sulfate: “some [believe] that it is not an anticonvulsant, presumably because the arrest of the convulsions and the prevention of their recurrence does not induce generalized central nervous system depression in mother or fetus.” We wish to note, parenthetically, that an intrinsic property of anticonvulsant medication is not the induction of “generalized central nervous.

Original languageEnglish (US)
Pages (from-to)1031-1032
Number of pages2
JournalArchives of Neurology
Issue number9
StatePublished - Jan 1 1990

All Science Journal Classification (ASJC) codes

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology


Dive into the research topics of 'A Continuing Controversy: Magnesium Sulfate in the Treatment of Eclamptic Seizures'. Together they form a unique fingerprint.

Cite this