A convenient synthesis of 14C‐cotinine from 14C‐nicotine

Dhimant Desai, Mirjana V. Djordjevic, Shantu Amin

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Abstract

A convenient synthesis with analytical monitoring of 14C‐cotinine is reported. 14C‐Nicotine was converted into 14C‐dibromocotinine hydrobromide perbromide. Debromination, achieved by using Zn dust/acetic acid, resulted in high yields (71%) of 14C‐cotinine.

Original languageEnglish (US)
Pages (from-to)259-263
Number of pages5
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Volume29
Issue number3
DOIs
Publication statusPublished - Jan 1 1991

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All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Radiology Nuclear Medicine and imaging
  • Drug Discovery
  • Spectroscopy
  • Organic Chemistry

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