A convergent total synthesis of the marine sponge alkaloid ageladine A via a strategic 6π-2-azatriene electrocyclization

Matthew L. Meketa, Steven M. Weinreb

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

A second generation total synthesis of the marine sponge metabolite ageladine A utilizing a biogenetically inspired 6π-2-azaelectrocyclization of triene 34 as the key step is performed to construct the imidazopyridine core of the metabolite.

Original languageEnglish (US)
Pages (from-to)9112-9119
Number of pages8
JournalTetrahedron
Volume63
Issue number37
DOIs
StatePublished - Sep 10 2007

Fingerprint

Porifera
Metabolites
Alkaloids
6pi-2-azatriene
Ageladine A

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Meketa, Matthew L. ; Weinreb, Steven M. / A convergent total synthesis of the marine sponge alkaloid ageladine A via a strategic 6π-2-azatriene electrocyclization. In: Tetrahedron. 2007 ; Vol. 63, No. 37. pp. 9112-9119.
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A convergent total synthesis of the marine sponge alkaloid ageladine A via a strategic 6π-2-azatriene electrocyclization. / Meketa, Matthew L.; Weinreb, Steven M.

In: Tetrahedron, Vol. 63, No. 37, 10.09.2007, p. 9112-9119.

Research output: Contribution to journalArticle

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