A decision-theoretic model of selection modulated intra-host antigenic variation for multi-strain pathogens

Ishanu Chattopadhyay, Sonia Mohinta, Asok Ray

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A decision-theoretic approach to modeling the response of multi-strain pathogens to humoral defense is investigated in this paper. The reported theory of language-measure theoretic optimal control is used to compute the optimal response of the invading pathogen. The model is validated by comparison of simulation results with in-vivo observations and contrasted with prominent existing modeling approaches.

Original languageEnglish (US)
Title of host publicationProceedings of the 2010 American Control Conference, ACC 2010
Pages454-459
Number of pages6
Publication statusPublished - Oct 18 2010
Event2010 American Control Conference, ACC 2010 - Baltimore, MD, United States
Duration: Jun 30 2010Jul 2 2010

Publication series

NameProceedings of the 2010 American Control Conference, ACC 2010

Other

Other2010 American Control Conference, ACC 2010
CountryUnited States
CityBaltimore, MD
Period6/30/107/2/10

    Fingerprint

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

Cite this

Chattopadhyay, I., Mohinta, S., & Ray, A. (2010). A decision-theoretic model of selection modulated intra-host antigenic variation for multi-strain pathogens. In Proceedings of the 2010 American Control Conference, ACC 2010 (pp. 454-459). [5530990] (Proceedings of the 2010 American Control Conference, ACC 2010).