A dramatic, objective antiandrogen withdrawal response: Case report and review of the literature

Yiu Keung Lau; Manpreet K. Chadha; Alan Litwin; Donald L. Trump

doi:10.1186/1756-8722-1-21

A dramatic, objective antiandrogen withdrawal response: Case report and review of the literature

Yiu Keung Lau, Manpreet K. Chadha, Alan Litwin, Donald L. Trump

Department of Radiology

Research output: Contribution to journal › Review article › peer-review

6 Citations (SciVal)

Abstract

Antiandrogen withdrawal response is an increasingly recognized entity in patients with metastatic prostate cancer. To our knowledge, there have been no reports describing a durable radiologic improvement along with prostate-specific antigen (PSA) with discontinuation of the antiandrogen agent bicalutamide. We report a case in which a dramatic decline of serum PSA levels associated with a dramatic improvement in radiologic disease was achieved with bicalutamide discontinuation.

Original language	English (US)
Article number	21
Journal	Journal of Hematology and Oncology
Volume	1
Issue number	1
DOIs	https://doi.org/10.1186/1756-8722-1-21
State	Published - 2008

All Science Journal Classification (ASJC) codes

Hematology
Molecular Biology
Oncology
Cancer Research

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10.1186/1756-8722-1-21

Cite this

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title = "A dramatic, objective antiandrogen withdrawal response: Case report and review of the literature",

abstract = "Antiandrogen withdrawal response is an increasingly recognized entity in patients with metastatic prostate cancer. To our knowledge, there have been no reports describing a durable radiologic improvement along with prostate-specific antigen (PSA) with discontinuation of the antiandrogen agent bicalutamide. We report a case in which a dramatic decline of serum PSA levels associated with a dramatic improvement in radiologic disease was achieved with bicalutamide discontinuation.",

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AU - Litwin, Alan

AU - Trump, Donald L.

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N2 - Antiandrogen withdrawal response is an increasingly recognized entity in patients with metastatic prostate cancer. To our knowledge, there have been no reports describing a durable radiologic improvement along with prostate-specific antigen (PSA) with discontinuation of the antiandrogen agent bicalutamide. We report a case in which a dramatic decline of serum PSA levels associated with a dramatic improvement in radiologic disease was achieved with bicalutamide discontinuation.

AB - Antiandrogen withdrawal response is an increasingly recognized entity in patients with metastatic prostate cancer. To our knowledge, there have been no reports describing a durable radiologic improvement along with prostate-specific antigen (PSA) with discontinuation of the antiandrogen agent bicalutamide. We report a case in which a dramatic decline of serum PSA levels associated with a dramatic improvement in radiologic disease was achieved with bicalutamide discontinuation.

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A dramatic, objective antiandrogen withdrawal response: Case report and review of the literature

Abstract

All Science Journal Classification (ASJC) codes

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