A Genomic Toolkit for the Mechanistic Dissection of Intractable Human Gut Bacteria

Jordan E. Bisanz, Paola Soto-Perez, Cecilia Noecker, Alexander A. Aksenov, Kathy N. Lam, Grace E. Kenney, Elizabeth N. Bess, Henry J. Haiser, Than S. Kyaw, Feiqiao B. Yu, Vayu M. Rekdal, Connie W.Y. Ha, Suzanne Devkota, Emily P. Balskus, Pieter C. Dorrestein, Emma Allen-Vercoe, Peter J. Turnbaugh

    Research output: Contribution to journalArticlepeer-review

    6 Citations (SciVal)

    Abstract

    Bisanz et al. focus on an in-depth study of Eggerthella lenta and the Coriobacteriia class: highly prevalent members of the human gut microbiota which have been poorly described. Through construction of a paired isolate and genome library, they validate tools for comparative genomic approaches to uncover effectors of xenobiotic metabolism and fitness.

    Original languageEnglish (US)
    Pages (from-to)1001-1013.e9
    JournalCell Host and Microbe
    Volume27
    Issue number6
    DOIs
    StatePublished - Jun 10 2020

    All Science Journal Classification (ASJC) codes

    • Parasitology
    • Microbiology
    • Virology

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