A growth factor from spinal cord

Thomas Jennings, R. David Jones, Allan Lipton

Research output: Contribution to journalArticle

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Abstract

Mitogenic activity is present at a variety of sites in the central nervous system. A growth factor was purified from neonatal bovine spinal cord. It has a pI of 9.5‐9.8 and a molecular weight of about 11,000 daltons. Spinal cord growth factor is a basic polypeptide that is inactivated by extremely acid or basic conditions. Its mobility on SDS polyacrylamide gels suggests that this factor is different from pituitary FGF and brain FGF‐1.

Original languageEnglish (US)
Pages (from-to)273-277
Number of pages5
JournalJournal of Cellular Physiology
Volume100
Issue number2
DOIs
Publication statusPublished - Aug 1979

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All Science Journal Classification (ASJC) codes

  • Physiology
  • Clinical Biochemistry
  • Cell Biology

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