A human dopamine transporter cDNA predicts reduced glycosylation, displays a novel repetitive element and provides racially-dimorphic TaqI RFLPs

David J. Vandenbergh; Antonio M. Persico; George R. Uhl

doi:10.1016/0169-328X(92)90165-8

A human dopamine transporter cDNA predicts reduced glycosylation, displays a novel repetitive element and provides racially-dimorphic TaqI RFLPs

David J. Vandenbergh, Antonio M. Persico, George R. Uhl

Research output: Contribution to journal › Article › peer-review

177 Scopus citations

Abstract

We describe a cDNA for the human dopamine transporter, which has been implicated in several human disorders linked to dopaminergic function. The cDNA predicts reduced glycosylation of the protein with respect to the rat transporter, as well as a novel repetitive element in the 3′ untranslated region of the cDNA. A TaqI RFLP is also reported that shows a race-specific difference in allelic frequencies.

Original language	English (US)
Pages (from-to)	161-166
Number of pages	6
Journal	Molecular Brain Research
Volume	15
Issue number	1-2
DOIs	https://doi.org/10.1016/0169-328X(92)90165-8
State	Published - Sep 1992

All Science Journal Classification (ASJC) codes

Molecular Biology
Cellular and Molecular Neuroscience

Access to Document

10.1016/0169-328X(92)90165-8

Cite this

@article{a1ad1d7c0e1140feb8abed0731659f2b,

title = "A human dopamine transporter cDNA predicts reduced glycosylation, displays a novel repetitive element and provides racially-dimorphic TaqI RFLPs",

abstract = "We describe a cDNA for the human dopamine transporter, which has been implicated in several human disorders linked to dopaminergic function. The cDNA predicts reduced glycosylation of the protein with respect to the rat transporter, as well as a novel repetitive element in the 3′ untranslated region of the cDNA. A TaqI RFLP is also reported that shows a race-specific difference in allelic frequencies.",

author = "Vandenbergh, {David J.} and Persico, {Antonio M.} and Uhl, {George R.}",

year = "1992",

month = sep,

doi = "10.1016/0169-328X(92)90165-8",

language = "English (US)",

volume = "15",

pages = "161--166",

journal = "Brain Research",

issn = "0006-8993",

publisher = "Elsevier",

number = "1-2",

}

TY - JOUR

T1 - A human dopamine transporter cDNA predicts reduced glycosylation, displays a novel repetitive element and provides racially-dimorphic TaqI RFLPs

AU - Vandenbergh, David J.

AU - Persico, Antonio M.

AU - Uhl, George R.

PY - 1992/9

Y1 - 1992/9

N2 - We describe a cDNA for the human dopamine transporter, which has been implicated in several human disorders linked to dopaminergic function. The cDNA predicts reduced glycosylation of the protein with respect to the rat transporter, as well as a novel repetitive element in the 3′ untranslated region of the cDNA. A TaqI RFLP is also reported that shows a race-specific difference in allelic frequencies.

AB - We describe a cDNA for the human dopamine transporter, which has been implicated in several human disorders linked to dopaminergic function. The cDNA predicts reduced glycosylation of the protein with respect to the rat transporter, as well as a novel repetitive element in the 3′ untranslated region of the cDNA. A TaqI RFLP is also reported that shows a race-specific difference in allelic frequencies.

UR - http://www.scopus.com/inward/record.url?scp=0026761657&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026761657&partnerID=8YFLogxK

U2 - 10.1016/0169-328X(92)90165-8

DO - 10.1016/0169-328X(92)90165-8

M3 - Article

C2 - 1359373

AN - SCOPUS:0026761657

VL - 15

SP - 161

EP - 166

JO - Brain Research

JF - Brain Research

SN - 0006-8993

IS - 1-2

ER -

A human dopamine transporter cDNA predicts reduced glycosylation, displays a novel repetitive element and provides racially-dimorphic TaqI RFLPs

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this