A large scale (N=102) functional neuroimaging study of error processing in a Go/NoGo task

Vaughn R. Steele, Eric D. Claus, Eyal Aharoni, Carla Harenski, Vince D. Calhoun, Godfrey Pearlson, Kent A. Kiehl

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


We report a functional magnetic resonance imaging (fMRI) study of 102 healthy participants who completed a demanding Go/NoGo task. The primary purpose of this study was to delineate the neural systems underlying responses to errors in a large sample. We identified a number of regions engaged during error processing including the anterior cingulate, left lateral prefrontal areas and bilateral inferior frontal gyrus, and the subthalamic nucleus. The power afforded by the large cohort enabled identification of regions not consistently measured during Go/NoGo tasks thus helping to incrementally refine our understanding of the neural correlates of error processing. With the present fMRI results, in combination with our previous exploration of response inhibition (Steele et al.), we outline a comprehensive set of regions associated with both response inhibition and error processing.

Original languageEnglish (US)
Pages (from-to)127-138
Number of pages12
JournalBehavioural Brain Research
StatePublished - Jul 15 2014

All Science Journal Classification (ASJC) codes

  • Behavioral Neuroscience


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