A longitudinal examination of physiological regulation in cocaine-exposed infants across the first 7 months of life

Pamela Schuetze, Rina D. Eiden, Ellen P. Edwards

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

This study examined the association between prenatal exposure to cocaine and physiological regulation across the first 7 months of age. Measures of respiratory sinus arrhythmia (RSA) were obtained from 169 (82 cocaine-exposed and 87 nonexposed) infants during baseline periods at 1 month and 7 months of age and during tasks designed to elicit positive and negative affect at 7 months of age. After controlling for maternal age, gestational age, and obstetrical risk, structural equation modeling indicated that the association between prenatal exposure to cocaine and baseline RSA at 7 months of age was direct even in the presence of an indirect effect through baseline RSA at 1 month of age. There were no indirect effects through maternal affect during mother-infant interactions assessed at 1 month of age. Analyses also indicated a direct association between prenatal exposure to cocaine and RSA regulation to negative affect at 7 months of age.

Original languageEnglish (US)
Pages (from-to)19-43
Number of pages25
JournalInfancy
Volume14
Issue number1
DOIs
StatePublished - 2009

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Developmental and Educational Psychology

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