A marker of early amacrine cell development in rat retina.

C. J. Barnstable, R. Hofstein, K. Akagawa

Research output: Contribution to journalArticlepeer-review

186 Scopus citations

Abstract

A monoclonal antibody, HPC-1, labels only amacrine and displaced amacrine cells in adult rat retina. Reactivity with displaced amacrine cells was demonstrated by double-label immunofluorescence with HPC-1 and ganglion cell-specific reagents. HPC-1 antibody reacts with a polypeptide of apparent molecular weight 35,000. HPC-1 antibody labels migrating amacrine cells in late embryonic retinas. The results define cell-specific gene expression in relation to migration of one subclass of CNS neurons.

Original languageEnglish (US)
Pages (from-to)286-290
Number of pages5
JournalBrain research
Volume352
Issue number2
StatePublished - Jun 1985

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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