A matter of life or death (or both): Understanding autophagy in cancer

William N. Hait, Shengkan Jin, Jin Ming Yang

Research output: Contribution to journalReview articlepeer-review

67 Scopus citations

Abstract

Autophagy is a highly conserved pathway that can be used for survival during nutrient and growth factor deprivation. Under certain circumstances, it seems that autophagy may serve as a pathway to cell death. Already, it is becoming increasingly clear that autophagy is involved in cancer formation, survival, and response to several forms of cancer treatments. A detailed understanding of how this pathway is regulated is now emerging and will allow translation of this information into new approaches to cancer treatment.

Original languageEnglish (US)
Pages (from-to)1961-1965
Number of pages5
JournalClinical Cancer Research
Volume12
Issue number7 I
DOIs
StatePublished - Apr 1 2006

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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