A matter of life or death (or both): Understanding autophagy in cancer

William N. Hait, Shengkan Jin, Jin Ming Yang

Research output: Contribution to journalReview article

66 Citations (Scopus)

Abstract

Autophagy is a highly conserved pathway that can be used for survival during nutrient and growth factor deprivation. Under certain circumstances, it seems that autophagy may serve as a pathway to cell death. Already, it is becoming increasingly clear that autophagy is involved in cancer formation, survival, and response to several forms of cancer treatments. A detailed understanding of how this pathway is regulated is now emerging and will allow translation of this information into new approaches to cancer treatment.

Original languageEnglish (US)
Pages (from-to)1961-1965
Number of pages5
JournalClinical Cancer Research
Volume12
Issue number7 I
DOIs
StatePublished - Apr 1 2006

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Autophagy
Neoplasms
Intercellular Signaling Peptides and Proteins
Cell Death
Food

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Hait, William N. ; Jin, Shengkan ; Yang, Jin Ming. / A matter of life or death (or both) : Understanding autophagy in cancer. In: Clinical Cancer Research. 2006 ; Vol. 12, No. 7 I. pp. 1961-1965.
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A matter of life or death (or both) : Understanding autophagy in cancer. / Hait, William N.; Jin, Shengkan; Yang, Jin Ming.

In: Clinical Cancer Research, Vol. 12, No. 7 I, 01.04.2006, p. 1961-1965.

Research output: Contribution to journalReview article

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