A mcirofluidic device of biodegradable porous silicon nanowires for size based capturing and releasing viruses

Yiqiu Xia, Siyang Zheng

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

A microfluidic device of porous silicon nanowire (PSNW) channel walls was fabricated as a point-of-care platform to capture nanoparticles (NPs) like viruses based on their sizes. PSNWs were synthesized on the bottom and sidewalls of the micro channels with metal-assisted etching. The space between PSNWs was controlled to capture NPs with a specific size. To enhance the capture rate, meandering channels were designed to increase the interaction between NPs and PSNWs by the Dean flow. With this system, we demonstrated label-free N5H2 avian influenza virus capture. In addition, virus can be released later and collected at the outlet by degrading PSNWs in PBS for 24 hours.

Original languageEnglish (US)
Title of host publication2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages444-447
Number of pages4
ISBN (Electronic)9781479989553
DOIs
StatePublished - Aug 5 2015
Event18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015 - Anchorage, United States
Duration: Jun 21 2015Jun 25 2015

Publication series

Name2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015

Other

Other18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015
CountryUnited States
CityAnchorage
Period6/21/156/25/15

All Science Journal Classification (ASJC) codes

  • Instrumentation
  • Electrical and Electronic Engineering

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    Xia, Y., & Zheng, S. (2015). A mcirofluidic device of biodegradable porous silicon nanowires for size based capturing and releasing viruses. In 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015 (pp. 444-447). [7180956] (2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/TRANSDUCERS.2015.7180956