A mechano-hydraulic model of intracranial pressure dynamics

Research output: Chapter in Book/Report/Conference proceedingConference contribution


The brain is a multi-phase mixture of cerebrospinal fluid (CSF), vasculature, and brain cells. The intracranial pressure (ICP) of the CSF can be monitored to assess patients suffering from serious neurological disorders, such as hydrocephalus and traumatic brain injury. However, the only reliable way to measure ICP is to drill a hole through the skull to insert a pressure sensor inside the brain. Therefore, it is necessary to create accurate mathematical models that couple the temporal dynamics of ICP with clinically-observable physiological parameters that can be measured non-invasively. In this paper, we present a new mechano-hydraulic mathematical model that allows one to study the dynamics arising from the coupling between the mechanics of brain, CSF circulation, and cerebral blood flow. We will study the dynamics of the model and examine domains of stability.

Original languageEnglish (US)
Title of host publicationMechanics of Biological Systems and Materials - Proceedings of the 2016 Annual Conference on Experimental and Applied Mechanics
EditorsChad S. Korach, Srinivasan Arjun Tekalur, Pablo Zavattieri
PublisherSpringer New York LLC
Number of pages8
ISBN (Print)9783319413501
StatePublished - Jan 1 2017
EventAnnual Conference and Exposition on Experimental and Applied Mechanics, 2016 - Orlando, United States
Duration: Jun 6 2016Jun 9 2016

Publication series

NameConference Proceedings of the Society for Experimental Mechanics Series
ISSN (Print)2191-5644
ISSN (Electronic)2191-5652


OtherAnnual Conference and Exposition on Experimental and Applied Mechanics, 2016
Country/TerritoryUnited States

All Science Journal Classification (ASJC) codes

  • Engineering(all)
  • Computational Mechanics
  • Mechanical Engineering


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