A mild, nonacidic method for the conversion of carboxylic esters into oxazolines

John H. Dod, Jihua Guan, Charles F. Schwender

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Conversion of carboxylic esters directly into amide alcohols is facilitated by use of base. Combined with a nonacidic cyclization of the intermediate amide alcohol this method allows formation of oxazolines under nonacidic conditions directly from the carboxylic esters.

Original languageEnglish (US)
Pages (from-to)1003-1008
Number of pages6
JournalSynthetic Communications
Volume23
Issue number7
DOIs
StatePublished - Apr 1 1993

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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