A model for linkage analysis with apomixis

Wei Hou, Shen Lin, Yao Li, Xiaoming Pang, Yanru Zeng, Rongling Wu

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Apomixis, or asexual reproduction through seeds, occurs in over 400 species of angiosperms. Although apomixis can favorably perpetuate desired genotypes through successive seed generation, it may also bring about some difficulty for linkage analysis and quantitative trait locus mapping. In this article, we explore the issue of how apomixis affects the precision and power of linkage analysis with molecular markers. We derive a statistical model for estimating the linkage between different markers when some progeny are derived from apomixis. The model was constructed within the maximum likelihood framework and implemented with the EM algorithm. A series of procedures are formulated to test the linkage of markers, the rate of apomixis, and the degree of genetic interference during meiosis. The model was examined and validated through simulation studies. The model will provide a tool for linkage mapping and evolutionary studies for plant species that undergo apomixis.

Original languageEnglish (US)
Pages (from-to)681-691
Number of pages11
JournalTheoretical And Applied Genetics
Volume123
Issue number5
DOIs
StatePublished - May 31 2011

Fingerprint

Apomixis
apomixis
linkage (genetics)
Seeds
Asexual Reproduction
Angiosperms
asexual reproduction
Chromosome Mapping
Quantitative Trait Loci
Meiosis
Statistical Models
crossover interference
seeds
statistical models
meiosis
chromosome mapping
Angiospermae
quantitative trait loci
Genotype
genetic markers

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Agronomy and Crop Science
  • Genetics

Cite this

Hou, Wei ; Lin, Shen ; Li, Yao ; Pang, Xiaoming ; Zeng, Yanru ; Wu, Rongling. / A model for linkage analysis with apomixis. In: Theoretical And Applied Genetics. 2011 ; Vol. 123, No. 5. pp. 681-691.
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Hou, W, Lin, S, Li, Y, Pang, X, Zeng, Y & Wu, R 2011, 'A model for linkage analysis with apomixis', Theoretical And Applied Genetics, vol. 123, no. 5, pp. 681-691. https://doi.org/10.1007/s00122-011-1618-4

A model for linkage analysis with apomixis. / Hou, Wei; Lin, Shen; Li, Yao; Pang, Xiaoming; Zeng, Yanru; Wu, Rongling.

In: Theoretical And Applied Genetics, Vol. 123, No. 5, 31.05.2011, p. 681-691.

Research output: Contribution to journalArticle

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