A model of the [FeFe] hydrogenase active site with a biologically relevant azadithiolate bridge: A spectroscopic and theoretical investigation

Özlen F. Erdem, Lennart Schwartz, Matthias Stein, Alexey Silakov, Sandeep Kaur-Ghumaan, Ping Huang, Sascha Ott, Edward J. Reijerse, Wolfgang Lubitz

Research output: Contribution to journalArticlepeer-review

109 Scopus citations

Abstract

Convincing evidence for the presence of a nitrogen atom in the dithiolate bridge of the active site of native [FeFe] hydrogenases (B) is provided by a spectroscopic, electrochemical, and theoretical study of a well-characterized structural mimic of the [FeFe] hydrogenase subcluster (picture: 14N matched-HYSCORE spectrum of the model compound A). This result should help to understand the mechanism of dihydrogen conversion and production.

Original languageEnglish (US)
Pages (from-to)1439-1443
Number of pages5
JournalAngewandte Chemie - International Edition
Volume50
Issue number6
DOIs
StatePublished - Feb 7 2011

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

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