A new approach to construct full-length glycosylphosphatidylinositols of parasitic protozoa and [4-deoxy-Man-III]-GPI analogues

Asif Ali, D. Channe Gowda, Ram A. Vishwakarma

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

A new [2 + 2 + 2] approach to construct GPI molecules through the efficient synthesis of glucosamine-inositol and tetramannose intermediates led to a total synthesis of a GPI-anchor of Trypanosoma cruzi, and also afforded a key intermediate for the synthesis of valuable [4-deoxy-Man-III]-GPI analogues.

Original languageEnglish (US)
Pages (from-to)519-521
Number of pages3
JournalChemical Communications
Issue number4
DOIs
StatePublished - Jan 28 2005

Fingerprint

Protozoa
Glycosylphosphatidylinositols
Glucosamine
Inositol
Anchors
Molecules

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

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A new approach to construct full-length glycosylphosphatidylinositols of parasitic protozoa and [4-deoxy-Man-III]-GPI analogues. / Ali, Asif; Gowda, D. Channe; Vishwakarma, Ram A.

In: Chemical Communications, No. 4, 28.01.2005, p. 519-521.

Research output: Contribution to journalArticle

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