A new approach to defining and diagnosing malnutrition in adult critical illness

Gordon Lee Jensen, Dara Wheeler

Research output: Contribution to journalReview article

41 Citations (Scopus)

Abstract

PURPOSE OF REVIEW: This review will highlight a new approach to defining malnutrition syndromes for critically ill adults that incorporates a modern understanding of the contributions of inflammatory response. A systematic approach to nutrition assessment is described to help support diagnosis. RECENT FINDINGS: Recent findings suggest that varying degrees of acute or chronic inflammation are key contributing factors in the pathogenesis of malnutrition in the setting of disease or injury. Newly proposed malnutrition syndromes include: 'starvation-associated malnutrition', when there is chronic starvation without inflammation; 'chronic disease-associated malnutrition', when inflammation is chronic and of mild to moderate degree; and 'acute disease or injury-associated malnutrition', when inflammation is acute and of severe degree. SUMMARY: Inflammation and malnutrition have an intimate interplay; the presence of inflammation contributes to the development of malnutrition and often limits the effectiveness of nutritional interventions. In turn, the associated malnutrition may blunt the effectiveness of medical therapies. A new approach to defining and diagnosing malnutrition syndromes can help to guide intervention and expected outcomes.

Original languageEnglish (US)
Pages (from-to)206-211
Number of pages6
JournalCurrent Opinion in Critical Care
Volume18
Issue number2
DOIs
StatePublished - Apr 1 2012

Fingerprint

Critical Illness
Malnutrition
Inflammation
Starvation
Nutrition Assessment
Wounds and Injuries
Acute Disease
Chronic Disease

All Science Journal Classification (ASJC) codes

  • Critical Care and Intensive Care Medicine

Cite this

Jensen, Gordon Lee ; Wheeler, Dara. / A new approach to defining and diagnosing malnutrition in adult critical illness. In: Current Opinion in Critical Care. 2012 ; Vol. 18, No. 2. pp. 206-211.
@article{b5620d14911340f58f89050c4d4a4b91,
title = "A new approach to defining and diagnosing malnutrition in adult critical illness",
abstract = "PURPOSE OF REVIEW: This review will highlight a new approach to defining malnutrition syndromes for critically ill adults that incorporates a modern understanding of the contributions of inflammatory response. A systematic approach to nutrition assessment is described to help support diagnosis. RECENT FINDINGS: Recent findings suggest that varying degrees of acute or chronic inflammation are key contributing factors in the pathogenesis of malnutrition in the setting of disease or injury. Newly proposed malnutrition syndromes include: 'starvation-associated malnutrition', when there is chronic starvation without inflammation; 'chronic disease-associated malnutrition', when inflammation is chronic and of mild to moderate degree; and 'acute disease or injury-associated malnutrition', when inflammation is acute and of severe degree. SUMMARY: Inflammation and malnutrition have an intimate interplay; the presence of inflammation contributes to the development of malnutrition and often limits the effectiveness of nutritional interventions. In turn, the associated malnutrition may blunt the effectiveness of medical therapies. A new approach to defining and diagnosing malnutrition syndromes can help to guide intervention and expected outcomes.",
author = "Jensen, {Gordon Lee} and Dara Wheeler",
year = "2012",
month = "4",
day = "1",
doi = "10.1097/MCC.0b013e328351683a",
language = "English (US)",
volume = "18",
pages = "206--211",
journal = "Current Opinion in Critical Care",
issn = "1070-5295",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

A new approach to defining and diagnosing malnutrition in adult critical illness. / Jensen, Gordon Lee; Wheeler, Dara.

In: Current Opinion in Critical Care, Vol. 18, No. 2, 01.04.2012, p. 206-211.

Research output: Contribution to journalReview article

TY - JOUR

T1 - A new approach to defining and diagnosing malnutrition in adult critical illness

AU - Jensen, Gordon Lee

AU - Wheeler, Dara

PY - 2012/4/1

Y1 - 2012/4/1

N2 - PURPOSE OF REVIEW: This review will highlight a new approach to defining malnutrition syndromes for critically ill adults that incorporates a modern understanding of the contributions of inflammatory response. A systematic approach to nutrition assessment is described to help support diagnosis. RECENT FINDINGS: Recent findings suggest that varying degrees of acute or chronic inflammation are key contributing factors in the pathogenesis of malnutrition in the setting of disease or injury. Newly proposed malnutrition syndromes include: 'starvation-associated malnutrition', when there is chronic starvation without inflammation; 'chronic disease-associated malnutrition', when inflammation is chronic and of mild to moderate degree; and 'acute disease or injury-associated malnutrition', when inflammation is acute and of severe degree. SUMMARY: Inflammation and malnutrition have an intimate interplay; the presence of inflammation contributes to the development of malnutrition and often limits the effectiveness of nutritional interventions. In turn, the associated malnutrition may blunt the effectiveness of medical therapies. A new approach to defining and diagnosing malnutrition syndromes can help to guide intervention and expected outcomes.

AB - PURPOSE OF REVIEW: This review will highlight a new approach to defining malnutrition syndromes for critically ill adults that incorporates a modern understanding of the contributions of inflammatory response. A systematic approach to nutrition assessment is described to help support diagnosis. RECENT FINDINGS: Recent findings suggest that varying degrees of acute or chronic inflammation are key contributing factors in the pathogenesis of malnutrition in the setting of disease or injury. Newly proposed malnutrition syndromes include: 'starvation-associated malnutrition', when there is chronic starvation without inflammation; 'chronic disease-associated malnutrition', when inflammation is chronic and of mild to moderate degree; and 'acute disease or injury-associated malnutrition', when inflammation is acute and of severe degree. SUMMARY: Inflammation and malnutrition have an intimate interplay; the presence of inflammation contributes to the development of malnutrition and often limits the effectiveness of nutritional interventions. In turn, the associated malnutrition may blunt the effectiveness of medical therapies. A new approach to defining and diagnosing malnutrition syndromes can help to guide intervention and expected outcomes.

UR - http://www.scopus.com/inward/record.url?scp=84858798434&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84858798434&partnerID=8YFLogxK

U2 - 10.1097/MCC.0b013e328351683a

DO - 10.1097/MCC.0b013e328351683a

M3 - Review article

VL - 18

SP - 206

EP - 211

JO - Current Opinion in Critical Care

JF - Current Opinion in Critical Care

SN - 1070-5295

IS - 2

ER -