A New Total Synthesis of the Fungal Toxin Slaframine

Richard A. Gobao, Martin L. Bremmer, Steven M. Weinreb

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Slaframine (1) has been synthesized from diene aldehyde 2. An intramolecular imino Diels-Alder reaction has been used to produce the indolizidine skeleton and to establish the requisite stereochemistry of this fungal metabolite.

Original languageEnglish (US)
Pages (from-to)7065-7068
Number of pages4
JournalJournal of the American Chemical Society
Volume104
Issue number25
DOIs
StatePublished - Jan 1 1982

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Indolizidines
Stereochemistry
Mycotoxins
Cycloaddition Reaction
Metabolites
Aldehydes
Skeleton
slaframine

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Gobao, Richard A. ; Bremmer, Martin L. ; Weinreb, Steven M. / A New Total Synthesis of the Fungal Toxin Slaframine. In: Journal of the American Chemical Society. 1982 ; Vol. 104, No. 25. pp. 7065-7068.
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A New Total Synthesis of the Fungal Toxin Slaframine. / Gobao, Richard A.; Bremmer, Martin L.; Weinreb, Steven M.

In: Journal of the American Chemical Society, Vol. 104, No. 25, 01.01.1982, p. 7065-7068.

Research output: Contribution to journalArticle

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