A new xenotransplantation model reveals tumor-initiating cells in cutaneous squamous cell carcinoma

Research output: Contribution to journalComment/debate

Abstract

Two articles by Patel et al. in this issue demonstrate reproducible, high-frequency xenografting of both primary human cutaneous squamous cell carcinoma (SCC) tissue and single-cell suspensions, as well as the existence of a small population of CD133 + tumor-initiating cells that are capable of regenerating the hierarchical organization and histology of the original tumor through multiple xenograft passages.

Original languageEnglish (US)
Pages (from-to)261-262
Number of pages2
JournalJournal of Investigative Dermatology
Volume132
Issue number2
DOIs
StatePublished - Jan 1 2012

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Heterologous Transplantation
Neoplastic Stem Cells
Heterografts
Tumors
Squamous Cell Carcinoma
Suspensions
Histology
Skin
Population
Neoplasms
Tissue
Epithelial Cells

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

Cite this

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title = "A new xenotransplantation model reveals tumor-initiating cells in cutaneous squamous cell carcinoma",
abstract = "Two articles by Patel et al. in this issue demonstrate reproducible, high-frequency xenografting of both primary human cutaneous squamous cell carcinoma (SCC) tissue and single-cell suspensions, as well as the existence of a small population of CD133 + tumor-initiating cells that are capable of regenerating the hierarchical organization and histology of the original tumor through multiple xenograft passages.",
author = "Glick, {Adam Bleier}",
year = "2012",
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}

A new xenotransplantation model reveals tumor-initiating cells in cutaneous squamous cell carcinoma. / Glick, Adam Bleier.

In: Journal of Investigative Dermatology, Vol. 132, No. 2, 01.01.2012, p. 261-262.

Research output: Contribution to journalComment/debate

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