TY - JOUR
T1 - A new xenotransplantation model reveals tumor-initiating cells in cutaneous squamous cell carcinoma
AU - Glick, Adam
N1 - Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2012/2
Y1 - 2012/2
N2 - Two articles by Patel et al. in this issue demonstrate reproducible, high-frequency xenografting of both primary human cutaneous squamous cell carcinoma (SCC) tissue and single-cell suspensions, as well as the existence of a small population of CD133 + tumor-initiating cells that are capable of regenerating the hierarchical organization and histology of the original tumor through multiple xenograft passages.
AB - Two articles by Patel et al. in this issue demonstrate reproducible, high-frequency xenografting of both primary human cutaneous squamous cell carcinoma (SCC) tissue and single-cell suspensions, as well as the existence of a small population of CD133 + tumor-initiating cells that are capable of regenerating the hierarchical organization and histology of the original tumor through multiple xenograft passages.
UR - http://www.scopus.com/inward/record.url?scp=84855970260&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84855970260&partnerID=8YFLogxK
U2 - 10.1038/jid.2011.327
DO - 10.1038/jid.2011.327
M3 - Comment/debate
C2 - 22241440
AN - SCOPUS:84855970260
VL - 132
SP - 261
EP - 262
JO - Journal of Investigative Dermatology
JF - Journal of Investigative Dermatology
SN - 0022-202X
IS - 2
ER -