Abstract
Two articles by Patel et al. in this issue demonstrate reproducible, high-frequency xenografting of both primary human cutaneous squamous cell carcinoma (SCC) tissue and single-cell suspensions, as well as the existence of a small population of CD133 + tumor-initiating cells that are capable of regenerating the hierarchical organization and histology of the original tumor through multiple xenograft passages.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 261-262 |
| Number of pages | 2 |
| Journal | Journal of Investigative Dermatology |
| Volume | 132 |
| Issue number | 2 |
| DOIs |
|
| State | Published - Feb 2012 |
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All Science Journal Classification (ASJC) codes
- Biochemistry
- Molecular Biology
- Dermatology
- Cell Biology
Cite this
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A new xenotransplantation model reveals tumor-initiating cells in cutaneous squamous cell carcinoma. / Glick, Adam.
In: Journal of Investigative Dermatology, Vol. 132, No. 2, 02.2012, p. 261-262.Research output: Contribution to journal › Comment/debate
TY - JOUR
T1 - A new xenotransplantation model reveals tumor-initiating cells in cutaneous squamous cell carcinoma
AU - Glick, Adam
PY - 2012/2
Y1 - 2012/2
N2 - Two articles by Patel et al. in this issue demonstrate reproducible, high-frequency xenografting of both primary human cutaneous squamous cell carcinoma (SCC) tissue and single-cell suspensions, as well as the existence of a small population of CD133 + tumor-initiating cells that are capable of regenerating the hierarchical organization and histology of the original tumor through multiple xenograft passages.
AB - Two articles by Patel et al. in this issue demonstrate reproducible, high-frequency xenografting of both primary human cutaneous squamous cell carcinoma (SCC) tissue and single-cell suspensions, as well as the existence of a small population of CD133 + tumor-initiating cells that are capable of regenerating the hierarchical organization and histology of the original tumor through multiple xenograft passages.
UR - http://www.scopus.com/inward/record.url?scp=84855970260&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84855970260&partnerID=8YFLogxK
U2 - 10.1038/jid.2011.327
DO - 10.1038/jid.2011.327
M3 - Comment/debate
C2 - 22241440
AN - SCOPUS:84855970260
VL - 132
SP - 261
EP - 262
JO - Journal of Investigative Dermatology
JF - Journal of Investigative Dermatology
SN - 0022-202X
IS - 2
ER -