A novel 3D micro membrane filtration device for capture viable rare circulating tumor cells from whole blood

Siyang Zheng, Henry K. Lin, Richard J. Cote, Yu Chong Tai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Abstract

Cancer is one of the most serious diseases facing human being. Improvement on cancer diagnostics has proved to be important for the outcome of cancer patients. We report here a novel micro membrane filtration device that captures rare circulating tumor cells from whole blood for early cancer diagnostics and treatment monitoring. The device is fabricated with multi layers of polymer material parylene-C. Tested with the model system, the device can capture tumor cells from whole blood with 86.5% capture efficiency. Different from previous membrane filtration devices, the cells are alive up to at least two weeks after isolation.

Original languageEnglish (US)
Title of host publication2008 Solid-State Sensors, Actuators, and Microsystems Workshop
EditorsLeland Spangler, Kimberly L. Turner
PublisherTransducer Research Foundation
Pages134-137
Number of pages4
ISBN (Electronic)0964002477, 9780964002470
StatePublished - Jan 1 2008
Event2008 Solid-State Sensors, Actuators, and Microsystems Workshop - Hilton Head Island, United States
Duration: Jun 1 2008Jun 5 2008

Publication series

NameTechnical Digest - Solid-State Sensors, Actuators, and Microsystems Workshop

Conference

Conference2008 Solid-State Sensors, Actuators, and Microsystems Workshop
CountryUnited States
CityHilton Head Island
Period6/1/086/5/08

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering
  • Electrical and Electronic Engineering
  • Hardware and Architecture

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  • Cite this

    Zheng, S., Lin, H. K., Cote, R. J., & Tai, Y. C. (2008). A novel 3D micro membrane filtration device for capture viable rare circulating tumor cells from whole blood. In L. Spangler, & K. L. Turner (Eds.), 2008 Solid-State Sensors, Actuators, and Microsystems Workshop (pp. 134-137). (Technical Digest - Solid-State Sensors, Actuators, and Microsystems Workshop). Transducer Research Foundation.