A novel ring cleavage reaction of oxazolines

Jeremy I. Levin, Steven M. Weinreb

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


An oxazoline can be cleanly converted to the parent carboxylic acid by treatment with NaOCl, followed by mild basic hydrolysis of the intermediate ester product(s).

Original languageEnglish (US)
Pages (from-to)2347-2350
Number of pages4
JournalTetrahedron Letters
Issue number23
StatePublished - Jan 1 1982

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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