A quantitative analysis of fish consumption and stroke risk

Colleen Bouzan, Joshua T. Cohen, William E. Connor, Penny Margaret Kris-Etherton, George M. Gray, Ariane König, Robert S. Lawrence, David A. Savitz, Steven M. Teutsch

Research output: Contribution to journalReview article

86 Citations (Scopus)

Abstract

Although a rich source of n-3 polyunsaturated fatty acids (PUFAs) that may confer multiple health benefits, some fish contain methyl mercury (MeHg), which may harm the developing fetus. U.S. government recommendations for women of childbearing age are to modify consumption of high-MeHg fish to reduce MeHg exposure, while recommendations encourage fish consumption among the general population because of the nutritional benefits. The Harvard Center for Risk Analysis convened an expert panel (see acknowledgments) to quantify the net impact of resulting hypothetical changes in fish consumption across the population. This paper estimates the impact of fish consumption on stroke risk. Other papers quantify coronary heart disease mortality risk and the impacts of both prenatal MeHg exposure and maternal intake of n-3 PUFAs on cognitive development. This analysis identified articles in a recent qualitative literature review that are appropriate for the development of a dose-response relationship between fish consumption and stroke risk. Studies had to satisfy quality criteria, quantify fish intake, and report the precision of the relative risk estimates. The analysis combined the relative risk results, weighting each proportionately to its precision. Six studies were identified as appropriate for inclusion in this analysis, including five prospective cohort studies and one case-control study (total of 24 exposure groups). Our analysis indicates that any fish consumption confers substantial relative risk reduction compared to no fish consumption (12% for the linear model), with the possibility that additional consumption confers incremental benefits (central estimate of 2.0% per serving per week).

Original languageEnglish (US)
Pages (from-to)347-352
Number of pages6
JournalAmerican Journal of Preventive Medicine
Volume29
Issue number4
DOIs
StatePublished - Jan 1 2005

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Fishes
Stroke
Omega-3 Fatty Acids
Maternal Exposure
Insurance Benefits
Risk Reduction Behavior
Mercury
Population
Coronary Disease
Case-Control Studies
Linear Models
Fetus
Cohort Studies
Prospective Studies
Mortality

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Public Health, Environmental and Occupational Health

Cite this

Bouzan, C., Cohen, J. T., Connor, W. E., Kris-Etherton, P. M., Gray, G. M., König, A., ... Teutsch, S. M. (2005). A quantitative analysis of fish consumption and stroke risk. American Journal of Preventive Medicine, 29(4), 347-352. https://doi.org/10.1016/j.amepre.2005.07.002
Bouzan, Colleen ; Cohen, Joshua T. ; Connor, William E. ; Kris-Etherton, Penny Margaret ; Gray, George M. ; König, Ariane ; Lawrence, Robert S. ; Savitz, David A. ; Teutsch, Steven M. / A quantitative analysis of fish consumption and stroke risk. In: American Journal of Preventive Medicine. 2005 ; Vol. 29, No. 4. pp. 347-352.
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Bouzan, C, Cohen, JT, Connor, WE, Kris-Etherton, PM, Gray, GM, König, A, Lawrence, RS, Savitz, DA & Teutsch, SM 2005, 'A quantitative analysis of fish consumption and stroke risk', American Journal of Preventive Medicine, vol. 29, no. 4, pp. 347-352. https://doi.org/10.1016/j.amepre.2005.07.002

A quantitative analysis of fish consumption and stroke risk. / Bouzan, Colleen; Cohen, Joshua T.; Connor, William E.; Kris-Etherton, Penny Margaret; Gray, George M.; König, Ariane; Lawrence, Robert S.; Savitz, David A.; Teutsch, Steven M.

In: American Journal of Preventive Medicine, Vol. 29, No. 4, 01.01.2005, p. 347-352.

Research output: Contribution to journalReview article

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