A reciprocal cross design to map the genetic architecture of complex traits in apomictic plants

Danni Yin, Xuli Zhu, Libo Jiang, Jian Zhang, Yanru Zeng, Rongling Wu

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Many higher plants of economic and biological importance undergo apomixis in which the maternal tissue of the ovule forms a seed, without experiencing meiosis and fertilization. This feature of apomixis has made it difficult to perform linkage mapping which relies on meiotic recombination. Here, we describe a computational model for mapping quantitative trait loci (QTLs) that control complex traits in apomictic plants. The model is founded on the mixture model-based likelihood in which maternal genotypes are dissolved into two possible components generated by meiotic and apomictic processes, respectively. The EM algorithm was implemented to discern meiotic and apomictic genotypes and, therefore, allow the marker-QTL linkage relationship to be estimated. By capitalizing on reciprocal crosses, the model is renovated to estimate and test imprinting effects of QTLs, providing a better gateway to characterize the genetic architecture of complex traits. The model was validated through computer simulation and further demonstrated for its usefulness by analyzing a real data for an apomictic woody plant. The model has for the first time provided a unique tool for genetic mapping in apomictic plants.

Original languageEnglish (US)
Pages (from-to)1360-1367
Number of pages8
JournalNew Phytologist
Volume205
Issue number3
DOIs
StatePublished - Feb 1 2015

Fingerprint

reciprocal crosses
Quantitative Trait Loci
Apomixis
quantitative trait loci
apomixis
Genotype
Mothers
Ovule
chromosome mapping
Internal-External Control
Chromosome Mapping
Meiosis
Fertilization
Computer Simulation
Genetic Recombination
Seeds
genomic imprinting
genotype
Economics
fertilization (reproduction)

All Science Journal Classification (ASJC) codes

  • Physiology
  • Plant Science

Cite this

Yin, Danni ; Zhu, Xuli ; Jiang, Libo ; Zhang, Jian ; Zeng, Yanru ; Wu, Rongling. / A reciprocal cross design to map the genetic architecture of complex traits in apomictic plants. In: New Phytologist. 2015 ; Vol. 205, No. 3. pp. 1360-1367.
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A reciprocal cross design to map the genetic architecture of complex traits in apomictic plants. / Yin, Danni; Zhu, Xuli; Jiang, Libo; Zhang, Jian; Zeng, Yanru; Wu, Rongling.

In: New Phytologist, Vol. 205, No. 3, 01.02.2015, p. 1360-1367.

Research output: Contribution to journalArticle

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