A retrospective analysis of the duration of oral antibiotic therapy for the treatment of acne among adolescents: Investigating practice gaps and potential cost-savings

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Background Duration of oral antibiotic therapy in acne has not been widely studied. Recent guidelines suggest it should be limited to 3 to 6 months. Objective We sought to compare the duration of oral antibiotic use with recent guidelines and determine the potential cost-savings related to shortened durations. Methods This is a retrospective cohort study from the MarketScan Commercial Claims and Encounters database. Claims data were used to determine duration and costs of antibiotic therapy. Results The mean course duration was 129 days. The majority (93%) of courses were less than 9 months. Among the 31,634 courses, 18,280 (57.8%) did not include concomitant topical retinoid therapy. The mean (95% confidence interval) duration with and without topical retinoid use was 133 (131.5-134.7) days and 127 (125.4-127.9) days, respectively. The mean excess direct cost of antibiotic treatment for longer than 6 months was $580.99/person. Limitations Claims cannot be attributed to a specific diagnosis or provider. The database does not provide information on acne severity. Conclusions Duration of antibiotic use is decreasing when compared with previous data. However, 5547 (17.53%) courses exceeded 6 months, highlighting an opportunity for reduced antibiotic use. If courses greater than 6 months were shortened to 6 months, savings would be $580.99/person.

Original languageEnglish (US)
Pages (from-to)70-76
Number of pages7
JournalJournal of the American Academy of Dermatology
Volume71
Issue number1
DOIs
StatePublished - Jan 1 2014

Fingerprint

Cost Savings
Acne Vulgaris
Anti-Bacterial Agents
Retinoids
Therapeutics
Databases
Guidelines
Health Care Costs
Professional Practice Gaps
Cohort Studies
Retrospective Studies
Confidence Intervals
Costs and Cost Analysis

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

@article{4eff16182464484985cf5121cc1d7395,
title = "A retrospective analysis of the duration of oral antibiotic therapy for the treatment of acne among adolescents: Investigating practice gaps and potential cost-savings",
abstract = "Background Duration of oral antibiotic therapy in acne has not been widely studied. Recent guidelines suggest it should be limited to 3 to 6 months. Objective We sought to compare the duration of oral antibiotic use with recent guidelines and determine the potential cost-savings related to shortened durations. Methods This is a retrospective cohort study from the MarketScan Commercial Claims and Encounters database. Claims data were used to determine duration and costs of antibiotic therapy. Results The mean course duration was 129 days. The majority (93{\%}) of courses were less than 9 months. Among the 31,634 courses, 18,280 (57.8{\%}) did not include concomitant topical retinoid therapy. The mean (95{\%} confidence interval) duration with and without topical retinoid use was 133 (131.5-134.7) days and 127 (125.4-127.9) days, respectively. The mean excess direct cost of antibiotic treatment for longer than 6 months was $580.99/person. Limitations Claims cannot be attributed to a specific diagnosis or provider. The database does not provide information on acne severity. Conclusions Duration of antibiotic use is decreasing when compared with previous data. However, 5547 (17.53{\%}) courses exceeded 6 months, highlighting an opportunity for reduced antibiotic use. If courses greater than 6 months were shortened to 6 months, savings would be $580.99/person.",
author = "Lee, {Young H.} and Guodong Liu and Thiboutot, {Diane M.} and Leslie, {Douglas L.} and Kirby, {Joslyn S.}",
year = "2014",
month = "1",
day = "1",
doi = "10.1016/j.jaad.2014.02.031",
language = "English (US)",
volume = "71",
pages = "70--76",
journal = "Journal of the American Academy of Dermatology",
issn = "0190-9622",
publisher = "Mosby Inc.",
number = "1",

}

TY - JOUR

T1 - A retrospective analysis of the duration of oral antibiotic therapy for the treatment of acne among adolescents

T2 - Investigating practice gaps and potential cost-savings

AU - Lee, Young H.

AU - Liu, Guodong

AU - Thiboutot, Diane M.

AU - Leslie, Douglas L.

AU - Kirby, Joslyn S.

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Background Duration of oral antibiotic therapy in acne has not been widely studied. Recent guidelines suggest it should be limited to 3 to 6 months. Objective We sought to compare the duration of oral antibiotic use with recent guidelines and determine the potential cost-savings related to shortened durations. Methods This is a retrospective cohort study from the MarketScan Commercial Claims and Encounters database. Claims data were used to determine duration and costs of antibiotic therapy. Results The mean course duration was 129 days. The majority (93%) of courses were less than 9 months. Among the 31,634 courses, 18,280 (57.8%) did not include concomitant topical retinoid therapy. The mean (95% confidence interval) duration with and without topical retinoid use was 133 (131.5-134.7) days and 127 (125.4-127.9) days, respectively. The mean excess direct cost of antibiotic treatment for longer than 6 months was $580.99/person. Limitations Claims cannot be attributed to a specific diagnosis or provider. The database does not provide information on acne severity. Conclusions Duration of antibiotic use is decreasing when compared with previous data. However, 5547 (17.53%) courses exceeded 6 months, highlighting an opportunity for reduced antibiotic use. If courses greater than 6 months were shortened to 6 months, savings would be $580.99/person.

AB - Background Duration of oral antibiotic therapy in acne has not been widely studied. Recent guidelines suggest it should be limited to 3 to 6 months. Objective We sought to compare the duration of oral antibiotic use with recent guidelines and determine the potential cost-savings related to shortened durations. Methods This is a retrospective cohort study from the MarketScan Commercial Claims and Encounters database. Claims data were used to determine duration and costs of antibiotic therapy. Results The mean course duration was 129 days. The majority (93%) of courses were less than 9 months. Among the 31,634 courses, 18,280 (57.8%) did not include concomitant topical retinoid therapy. The mean (95% confidence interval) duration with and without topical retinoid use was 133 (131.5-134.7) days and 127 (125.4-127.9) days, respectively. The mean excess direct cost of antibiotic treatment for longer than 6 months was $580.99/person. Limitations Claims cannot be attributed to a specific diagnosis or provider. The database does not provide information on acne severity. Conclusions Duration of antibiotic use is decreasing when compared with previous data. However, 5547 (17.53%) courses exceeded 6 months, highlighting an opportunity for reduced antibiotic use. If courses greater than 6 months were shortened to 6 months, savings would be $580.99/person.

UR - http://www.scopus.com/inward/record.url?scp=84903279007&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84903279007&partnerID=8YFLogxK

U2 - 10.1016/j.jaad.2014.02.031

DO - 10.1016/j.jaad.2014.02.031

M3 - Article

C2 - 24725476

AN - SCOPUS:84903279007

VL - 71

SP - 70

EP - 76

JO - Journal of the American Academy of Dermatology

JF - Journal of the American Academy of Dermatology

SN - 0190-9622

IS - 1

ER -