A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene)

N. Malvadkar, P. Kao, H. Wang, D. L. Allara, Melik C. Demirel

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

Surface enhanced Raman spectroscopy (SERS), as the basis of rapid and reliable biosensing techniques, has significant advantages of minimal sample preparation and ease of operation compared to other culture amplification methods. However, applications to biomedical problems have lagged because current substrates lack highly reproducible SERS responses to biological samples. Recently, we have developed nanostructured polymer substrates that can provide a highly uniform and reproducible nanoscale roughness. In this article, we studied advanced types of SERS substrates that will provide a highly uniform and reproducible "fingerprint" of E.Coli on a nanostructured polymer substrate coated with SERS active metals.

Original languageEnglish (US)
Title of host publicationTechnical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008
Pages555-557
Number of pages3
Volume2
StatePublished - 2008
Event2008 NSTI Nanotechnology Conference and Trade Show, NSTI Nanotech 2008 Joint Meeting, Nanotechnology 2008 - Quebec City, QC, United States
Duration: Jun 1 2008Jun 5 2008

Other

Other2008 NSTI Nanotechnology Conference and Trade Show, NSTI Nanotech 2008 Joint Meeting, Nanotechnology 2008
CountryUnited States
CityQuebec City, QC
Period6/1/086/5/08

Fingerprint

Escherichia coli
Raman spectroscopy
Substrates
Polymers
Amplification
Surface roughness
Metals

All Science Journal Classification (ASJC) codes

  • Mechanical Engineering

Cite this

Malvadkar, N., Kao, P., Wang, H., Allara, D. L., & Demirel, M. C. (2008). A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene). In Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008 (Vol. 2, pp. 555-557)
Malvadkar, N. ; Kao, P. ; Wang, H. ; Allara, D. L. ; Demirel, Melik C. / A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene). Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008. Vol. 2 2008. pp. 555-557
@inproceedings{86c03b409395411cbb1fe4cd6932c817,
title = "A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene)",
abstract = "Surface enhanced Raman spectroscopy (SERS), as the basis of rapid and reliable biosensing techniques, has significant advantages of minimal sample preparation and ease of operation compared to other culture amplification methods. However, applications to biomedical problems have lagged because current substrates lack highly reproducible SERS responses to biological samples. Recently, we have developed nanostructured polymer substrates that can provide a highly uniform and reproducible nanoscale roughness. In this article, we studied advanced types of SERS substrates that will provide a highly uniform and reproducible {"}fingerprint{"} of E.Coli on a nanostructured polymer substrate coated with SERS active metals.",
author = "N. Malvadkar and P. Kao and H. Wang and Allara, {D. L.} and Demirel, {Melik C.}",
year = "2008",
language = "English (US)",
isbn = "9781420085075",
volume = "2",
pages = "555--557",
booktitle = "Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008",

}

Malvadkar, N, Kao, P, Wang, H, Allara, DL & Demirel, MC 2008, A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene). in Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008. vol. 2, pp. 555-557, 2008 NSTI Nanotechnology Conference and Trade Show, NSTI Nanotech 2008 Joint Meeting, Nanotechnology 2008, Quebec City, QC, United States, 6/1/08.

A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene). / Malvadkar, N.; Kao, P.; Wang, H.; Allara, D. L.; Demirel, Melik C.

Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008. Vol. 2 2008. p. 555-557.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

TY - GEN

T1 - A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene)

AU - Malvadkar, N.

AU - Kao, P.

AU - Wang, H.

AU - Allara, D. L.

AU - Demirel, Melik C.

PY - 2008

Y1 - 2008

N2 - Surface enhanced Raman spectroscopy (SERS), as the basis of rapid and reliable biosensing techniques, has significant advantages of minimal sample preparation and ease of operation compared to other culture amplification methods. However, applications to biomedical problems have lagged because current substrates lack highly reproducible SERS responses to biological samples. Recently, we have developed nanostructured polymer substrates that can provide a highly uniform and reproducible nanoscale roughness. In this article, we studied advanced types of SERS substrates that will provide a highly uniform and reproducible "fingerprint" of E.Coli on a nanostructured polymer substrate coated with SERS active metals.

AB - Surface enhanced Raman spectroscopy (SERS), as the basis of rapid and reliable biosensing techniques, has significant advantages of minimal sample preparation and ease of operation compared to other culture amplification methods. However, applications to biomedical problems have lagged because current substrates lack highly reproducible SERS responses to biological samples. Recently, we have developed nanostructured polymer substrates that can provide a highly uniform and reproducible nanoscale roughness. In this article, we studied advanced types of SERS substrates that will provide a highly uniform and reproducible "fingerprint" of E.Coli on a nanostructured polymer substrate coated with SERS active metals.

UR - http://www.scopus.com/inward/record.url?scp=52649144777&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=52649144777&partnerID=8YFLogxK

M3 - Conference contribution

SN - 9781420085075

SN - 9781420085044

VL - 2

SP - 555

EP - 557

BT - Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008

ER -

Malvadkar N, Kao P, Wang H, Allara DL, Demirel MC. A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene). In Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008. Vol. 2. 2008. p. 555-557