A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene)

N. Malvadkar, P. Kao, H. Wang, D. L. Allara, M. C. Demirel

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

Surface enhanced Raman spectroscopy (SERS), as the basis of rapid and reliable biosensing techniques, has significant advantages of minimal sample preparation and ease of operation compared to other culture amplification methods. However, applications to biomedical problems have lagged because current substrates lack highly reproducible SERS responses to biological samples. Recently, we have developed nanostructured polymer substrates that can provide a highly uniform and reproducible nanoscale roughness. In this article, we studied advanced types of SERS substrates that will provide a highly uniform and reproducible "fingerprint" of E.Coli on a nanostructured polymer substrate coated with SERS active metals.

Original languageEnglish (US)
Title of host publicationTechnical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008
Pages555-557
Number of pages3
Publication statusPublished - Oct 1 2008
Event2008 NSTI Nanotechnology Conference and Trade Show, NSTI Nanotech 2008 Joint Meeting, Nanotechnology 2008 - Quebec City, QC, United States
Duration: Jun 1 2008Jun 5 2008

Publication series

NameTechnical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008
Volume2

Other

Other2008 NSTI Nanotechnology Conference and Trade Show, NSTI Nanotech 2008 Joint Meeting, Nanotechnology 2008
CountryUnited States
CityQuebec City, QC
Period6/1/086/5/08

    Fingerprint

All Science Journal Classification (ASJC) codes

  • Mechanical Engineering

Cite this

Malvadkar, N., Kao, P., Wang, H., Allara, D. L., & Demirel, M. C. (2008). A SERS substrate for detection of E.Coli on nanostructured poly(p-xylylene). In Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008 (pp. 555-557). (Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008; Vol. 2).