A study in which one subunit of the oscillatory network of the leech Hirudo medicinalis was reconstructed on a cell-by-cell, synapse-by-synapse basis using IC-based neural elements is discussed. The network consists of 11 cells in which 34 distinct multicellular oscillators are embedded. In functional tests, the circuit displayed rhythms and waveforms that closely resembled robustness over a broad range of intracellular and synaptic parameters. The comprehensive nature of the neuronal element's design and the efficiency afforded by VLSI technology has greatly facilitated the endeavor of modeling neuronal networks and processes in analog electronic circuitry.
All Science Journal Classification (ASJC) codes
- Biomedical Engineering