TY - JOUR
T1 - A single simulation platform for hybrid photoacoustic and RF-acoustic computed tomography
AU - Fadden, Christopher
AU - Kothapalli, Sri Rajasekhar
N1 - Funding Information:
Funding: The authors would like to thank the NIH for funding this work under NIH-NIBIB 4R00EB017729 (Sri-Rajasekhar Kothapalli) and PennState Hershey Center Institute Cancer Startup Funds (Sri-Rajasekhar Kothapalli).
Publisher Copyright:
© 2018 by the authors.
PY - 2018/9/6
Y1 - 2018/9/6
N2 - In recent years, multimodal thermoacoustic imaging has demonstrated superior imaging quality compared to other emerging modalities. It provides functional and molecular information, arising due to electromagnetic absorption contrast, at ultrasonic resolution using inexpensive and non-ionizing imaging methods. The development of optical- as well as radio frequency (RF)-induced thermoacoustic imaging systems would benefit from reliable numerical simulations. To date, most numerical models use a combination of different software in order to model the hybrid thermoacoustic phenomenon. Here, we demonstrate the use of a single open source finite element software platform (ONELAB) for photo- and RF-acoustic computed tomography. The solutions of the optical diffusion equation, frequency domain Maxwell's equations, and time-domain wave equation are used to solve the optical, electromagnetic, and acoustic propagation problems, respectively, in ONELAB. The results on a test homogeneous phantom and an approximate breast phantom confirm that ONELAB is a very effective software for both photo- and RF-acoustic simulations, and invaluable for developing new reconstruction algorithms and hardware systems.
AB - In recent years, multimodal thermoacoustic imaging has demonstrated superior imaging quality compared to other emerging modalities. It provides functional and molecular information, arising due to electromagnetic absorption contrast, at ultrasonic resolution using inexpensive and non-ionizing imaging methods. The development of optical- as well as radio frequency (RF)-induced thermoacoustic imaging systems would benefit from reliable numerical simulations. To date, most numerical models use a combination of different software in order to model the hybrid thermoacoustic phenomenon. Here, we demonstrate the use of a single open source finite element software platform (ONELAB) for photo- and RF-acoustic computed tomography. The solutions of the optical diffusion equation, frequency domain Maxwell's equations, and time-domain wave equation are used to solve the optical, electromagnetic, and acoustic propagation problems, respectively, in ONELAB. The results on a test homogeneous phantom and an approximate breast phantom confirm that ONELAB is a very effective software for both photo- and RF-acoustic simulations, and invaluable for developing new reconstruction algorithms and hardware systems.
UR - http://www.scopus.com/inward/record.url?scp=85053053343&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85053053343&partnerID=8YFLogxK
U2 - 10.3390/app8091568
DO - 10.3390/app8091568
M3 - Article
C2 - 31304045
AN - SCOPUS:85053053343
VL - 8
JO - Applied Sciences (Switzerland)
JF - Applied Sciences (Switzerland)
SN - 2076-3417
IS - 9
M1 - 1568
ER -