A stereoselective 3-endo-alkyl-5,6-dehydroisoquinuclidine synthesis.

Grant R. Krow, James T. Carey, Kevin Charles Cannon, Kenneth J. Henz

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Cycloaddition of N-carbethoxy-2-alkyl-1,2-dihydropyridines 4 with phenylvinylsulfone 5 provides adducts 6, which upon desulfonylation afford stereoselectively N-carbethoxy-3-endo- alkyl-5,6-dehydroisoquinuclidines 1.

Original languageEnglish (US)
Pages (from-to)2527-2528
Number of pages2
JournalTetrahedron Letters
Volume23
Issue number25
DOIs
StatePublished - Jan 1 1982

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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