A stereoselective 3-endo-alkyl-5,6-dehydroisoquinuclidine synthesis.

Grant R. Krow, James T. Carey, Kevin Charles Cannon, Kenneth J. Henz

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Cycloaddition of N-carbethoxy-2-alkyl-1,2-dihydropyridines 4 with phenylvinylsulfone 5 provides adducts 6, which upon desulfonylation afford stereoselectively N-carbethoxy-3-endo- alkyl-5,6-dehydroisoquinuclidines 1.

Original languageEnglish (US)
Pages (from-to)2527-2528
Number of pages2
JournalTetrahedron Letters
Volume23
Issue number25
DOIs
StatePublished - Jan 1 1982

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Dihydropyridines
Cycloaddition
Cycloaddition Reaction

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Krow, Grant R. ; Carey, James T. ; Cannon, Kevin Charles ; Henz, Kenneth J. / A stereoselective 3-endo-alkyl-5,6-dehydroisoquinuclidine synthesis. In: Tetrahedron Letters. 1982 ; Vol. 23, No. 25. pp. 2527-2528.
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A stereoselective 3-endo-alkyl-5,6-dehydroisoquinuclidine synthesis. / Krow, Grant R.; Carey, James T.; Cannon, Kevin Charles; Henz, Kenneth J.

In: Tetrahedron Letters, Vol. 23, No. 25, 01.01.1982, p. 2527-2528.

Research output: Contribution to journalArticle

TY - JOUR

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AU - Krow, Grant R.

AU - Carey, James T.

AU - Cannon, Kevin Charles

AU - Henz, Kenneth J.

PY - 1982/1/1

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AB - Cycloaddition of N-carbethoxy-2-alkyl-1,2-dihydropyridines 4 with phenylvinylsulfone 5 provides adducts 6, which upon desulfonylation afford stereoselectively N-carbethoxy-3-endo- alkyl-5,6-dehydroisoquinuclidines 1.

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