A stimulated rate of gluconeogenesis in perfused livers of hypophysectomized rats

E. L. Tolman, L. E. Metzger, L. S. Jefferson

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Production of glucose and urea by livers of hypophysectomized rats was twice that by livers of normal rats when both were perfused with medium containing amino acids at either one or ten times their normal plasma concentrations. This suggested a stimulated rate of gluconeogenesis in the livers of hypophysectomized rats. Increased rates of conversion of 14C-alanine and 14C-lactate to glucose were observed in livers of these rats.

Original languageEnglish (US)
Pages (from-to)294-298
Number of pages5
JournalBiochemical and Biophysical Research Communications
Volume41
Issue number2
DOIs
StatePublished - Oct 23 1970

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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