A synaptogenic pacing cell line

Ricardo Silva, Eric Barrett, Jamie Kowal, Ji Sung Kim, Harry Allcock, Roger Gaumond

Research output: Contribution to conferencePaperpeer-review

Abstract

The SK-N-BE(2c) is an I-type neuroblastoma that develops a strong pacing electrical response over time. This response is likely the result of a developing interconnected network, such that the regular pacemaker-like firing of individual cells becomes synchronous over time forming a Multi Unit Spikes signal (MUS). Immuno-fluorescence was used to show the presence of pre and postsynaptic markers, suggesting that MUS are the result of networking. Hence this cell line could prove as a useful model for synaptic dopaminergic pacing cell systems.

Original languageEnglish (US)
Pages260-261
Number of pages2
DOIs
StatePublished - Dec 1 2005
Event2nd International IEEE EMBS Conference on Neural Engineering, 2005 - Arlington, VA, United States
Duration: Mar 16 2005Mar 19 2005

Other

Other2nd International IEEE EMBS Conference on Neural Engineering, 2005
Country/TerritoryUnited States
CityArlington, VA
Period3/16/053/19/05

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Fingerprint

Dive into the research topics of 'A synaptogenic pacing cell line'. Together they form a unique fingerprint.

Cite this