TY - JOUR
T1 - A warning on the use of radical traps as a test for radical mechanisms
T2 - They react with palladium hydrido complexes
AU - Albéniz, Ana C.
AU - Espinet, Pablo
AU - López-Fernández, Raquel
AU - Sen, Ayusman
PY - 2002/9/25
Y1 - 2002/9/25
N2 - Typical radical traps (galvinoxyl, TEMPO, DPPH) react with palladium hydrides, sometimes at rates competitive with those of palladium hydride catalyzed reactions that follow an insertion mechanism (for example, alkene isomerization). Thus, positive results for radical reaction tests can be misleading. The complexes with more polarizable (neutral complexes rather than cationic) and more accessible hydrides, and the less sterically protected radical traps, react faster.
AB - Typical radical traps (galvinoxyl, TEMPO, DPPH) react with palladium hydrides, sometimes at rates competitive with those of palladium hydride catalyzed reactions that follow an insertion mechanism (for example, alkene isomerization). Thus, positive results for radical reaction tests can be misleading. The complexes with more polarizable (neutral complexes rather than cationic) and more accessible hydrides, and the less sterically protected radical traps, react faster.
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U2 - 10.1021/ja0271126
DO - 10.1021/ja0271126
M3 - Article
C2 - 12236736
AN - SCOPUS:0037174382
SN - 0002-7863
VL - 124
SP - 11278
EP - 11279
JO - Journal of the American Chemical Society
JF - Journal of the American Chemical Society
IS - 38
ER -