Abacavir methanol 2.5-solvate

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Abstract

The structure of abacavir (systematic name: {(1S,4R)-4-[2-amino-6-(cyclo- propyl-amino)-9H-purin-9-yl]cyclo-pent-2-en-1-yl}methanol), C14H 18N6O·2.5CH3OH, consists of hydrogen-bonded ribbons which are further held together by additional hydrogen bonds involving the hydroxyl group and two N atoms on an adjacent purine. The asymmetric unit also contains 2.5 mol-ecules of methanol solvate which were grossly disordered and were excluded using SQUEEZE subroutine in PLATON [Spek, (2009). Acta Cryst. D65, 148-155].

Original languageEnglish (US)
Pages (from-to)o1937
JournalActa Crystallographica Section E: Structure Reports Online
Volume65
Issue number8
DOIs
StatePublished - 2009

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics

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