Abdominal wall endometriosis in a rhesus macaque (Macaca mulatta)

Hannah Atkins, David L. Caudell, A. Robert Hutchison, Andre C. LeGrande, Nancy D. Kock

Research output: Contribution to journalArticle

Abstract

Endometriosis is the presence of endometrium outside of the uterus. Although endometriosis occurs in both pelvic and extrapelvic locations, extrapelvic locations are less common. The development of abdominal wall or incisional endometriosis in women is associated with gynecologic surgeries and is often misdiagnosed. Because they naturally develop endometriosis similar to women, Old World NHP, including rhesus macaques, provide excellent opportunities for studying endometriosis. Here, we describe a case of abdominal wall endometriosis in a rhesus macaque that had undergone cesarean section. Microscopically, the tissue consisted of pseudocolumnar epithelium-lined glands within a decidualized stroma, which dissected through the abdominal wall musculature and into the adjacent subcutaneous tissue. The stroma was strongly positive for vimentin and CD10 but was rarely, weakly positive for estrogen receptors and negative for progesterone. Close examination of extrapelvic endometriosis in rhesus macaques and other NHP may promote increased understanding of endometriosis in women.

Original languageEnglish (US)
Pages (from-to)277-280
Number of pages4
JournalComparative Medicine
Volume67
Issue number3
StatePublished - Jun 1 2017

Fingerprint

Abdominal Wall
Endometriosis
Macaca mulatta
Tissue
Vimentin
Estrogen Receptors
Surgery
Progesterone
cesarean section
vimentin
endometrium
uterus
progesterone
epithelium
surgery
Gynecologic Surgical Procedures
Subcutaneous Tissue
Endometrium
Diagnostic Errors
Cesarean Section

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • veterinary(all)

Cite this

Atkins, H., Caudell, D. L., Hutchison, A. R., LeGrande, A. C., & Kock, N. D. (2017). Abdominal wall endometriosis in a rhesus macaque (Macaca mulatta). Comparative Medicine, 67(3), 277-280.
Atkins, Hannah ; Caudell, David L. ; Hutchison, A. Robert ; LeGrande, Andre C. ; Kock, Nancy D. / Abdominal wall endometriosis in a rhesus macaque (Macaca mulatta). In: Comparative Medicine. 2017 ; Vol. 67, No. 3. pp. 277-280.
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Atkins, H, Caudell, DL, Hutchison, AR, LeGrande, AC & Kock, ND 2017, 'Abdominal wall endometriosis in a rhesus macaque (Macaca mulatta)', Comparative Medicine, vol. 67, no. 3, pp. 277-280.

Abdominal wall endometriosis in a rhesus macaque (Macaca mulatta). / Atkins, Hannah; Caudell, David L.; Hutchison, A. Robert; LeGrande, Andre C.; Kock, Nancy D.

In: Comparative Medicine, Vol. 67, No. 3, 01.06.2017, p. 277-280.

Research output: Contribution to journalArticle

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Atkins H, Caudell DL, Hutchison AR, LeGrande AC, Kock ND. Abdominal wall endometriosis in a rhesus macaque (Macaca mulatta). Comparative Medicine. 2017 Jun 1;67(3):277-280.