Abstract
Endometriosis is the presence of endometrium outside of the uterus. Although endometriosis occurs in both pelvic and extrapelvic locations, extrapelvic locations are less common. The development of abdominal wall or incisional endometriosis in women is associated with gynecologic surgeries and is often misdiagnosed. Because they naturally develop endometriosis similar to women, Old World NHP, including rhesus macaques, provide excellent opportunities for studying endometriosis. Here, we describe a case of abdominal wall endometriosis in a rhesus macaque that had undergone cesarean section. Microscopically, the tissue consisted of pseudocolumnar epithelium-lined glands within a decidualized stroma, which dissected through the abdominal wall musculature and into the adjacent subcutaneous tissue. The stroma was strongly positive for vimentin and CD10 but was rarely, weakly positive for estrogen receptors and negative for progesterone. Close examination of extrapelvic endometriosis in rhesus macaques and other NHP may promote increased understanding of endometriosis in women.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 277-280 |
| Number of pages | 4 |
| Journal | Comparative Medicine |
| Volume | 67 |
| Issue number | 3 |
| State | Published - Jun 2017 |
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All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)
- veterinary(all)
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Abdominal wall endometriosis in a rhesus macaque (Macaca mulatta). / Atkins, Hannah M.; Caudell, David L.; Hutchison, A. Robert; LeGrande, Andre C.; Kock, Nancy D.
In: Comparative Medicine, Vol. 67, No. 3, 06.2017, p. 277-280.Research output: Contribution to journal › Article
TY - JOUR
T1 - Abdominal wall endometriosis in a rhesus macaque (Macaca mulatta)
AU - Atkins, Hannah M.
AU - Caudell, David L.
AU - Hutchison, A. Robert
AU - LeGrande, Andre C.
AU - Kock, Nancy D.
PY - 2017/6
Y1 - 2017/6
N2 - Endometriosis is the presence of endometrium outside of the uterus. Although endometriosis occurs in both pelvic and extrapelvic locations, extrapelvic locations are less common. The development of abdominal wall or incisional endometriosis in women is associated with gynecologic surgeries and is often misdiagnosed. Because they naturally develop endometriosis similar to women, Old World NHP, including rhesus macaques, provide excellent opportunities for studying endometriosis. Here, we describe a case of abdominal wall endometriosis in a rhesus macaque that had undergone cesarean section. Microscopically, the tissue consisted of pseudocolumnar epithelium-lined glands within a decidualized stroma, which dissected through the abdominal wall musculature and into the adjacent subcutaneous tissue. The stroma was strongly positive for vimentin and CD10 but was rarely, weakly positive for estrogen receptors and negative for progesterone. Close examination of extrapelvic endometriosis in rhesus macaques and other NHP may promote increased understanding of endometriosis in women.
AB - Endometriosis is the presence of endometrium outside of the uterus. Although endometriosis occurs in both pelvic and extrapelvic locations, extrapelvic locations are less common. The development of abdominal wall or incisional endometriosis in women is associated with gynecologic surgeries and is often misdiagnosed. Because they naturally develop endometriosis similar to women, Old World NHP, including rhesus macaques, provide excellent opportunities for studying endometriosis. Here, we describe a case of abdominal wall endometriosis in a rhesus macaque that had undergone cesarean section. Microscopically, the tissue consisted of pseudocolumnar epithelium-lined glands within a decidualized stroma, which dissected through the abdominal wall musculature and into the adjacent subcutaneous tissue. The stroma was strongly positive for vimentin and CD10 but was rarely, weakly positive for estrogen receptors and negative for progesterone. Close examination of extrapelvic endometriosis in rhesus macaques and other NHP may promote increased understanding of endometriosis in women.
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UR - http://www.scopus.com/inward/citedby.url?scp=85021642528&partnerID=8YFLogxK
M3 - Article
C2 - 28662757
AN - SCOPUS:85021642528
VL - 67
SP - 277
EP - 280
JO - Comparative Medicine
JF - Comparative Medicine
SN - 1532-0820
IS - 3
ER -