Absolute copy number and relative change in determinations of human immunodeficiency virus type 1 RNA in plasma: Effect of an external standard on kit comparisons

Donald Brambilla, Sheila Leung, Judy Lew, John Todd, Steven Herman, Mike Cronin, David E. Shapiro, James Bremer, Celine Hanson, George V. Hillyer, George D. Mcsherry, Rhoda S. Sperling, Robert W. Coombs, Patricia S. Reichelderfer

Research output: Contribution to journalArticlepeer-review

41 Scopus citations

Abstract

Use of a common set of human immunodeficiency virus type 1 (HIV-1) RNA standards eliminated differences among absolute HIV-1 RNA copy number made with three commercially available assays. The relative changes in the viral RNA levels determinated by the commercial assays were similar and were unaffected by the use of a common set of standards.

Original languageEnglish (US)
Pages (from-to)311-314
Number of pages4
JournalJournal of clinical microbiology
Volume36
Issue number1
DOIs
StatePublished - Jan 1998

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)

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