The chlorination of pyrrole with N‐chloroacetanilide was catalyzed by acetic acid. Transfer of Cl+ occurred directly to the α and β positions of pyrrole and a mixture of 2‐chloro‐, 3‐chloro‐ and 2,5,‐dichloropyrrole was formed. The α↗β ratio was 10:1 under competitive conditions.
All Science Journal Classification (ASJC) codes
- Organic Chemistry