Acoustofluidic Rotational Manipulation of Cells and Organisms Using Oscillating Solid Structures

Adem Ozcelik, Nitesh Nama, Po Hsun Huang, Murat Kaynak, Melanie R. McReynolds, Wendy Hanna-Rose, Tony Jun Huang

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

A polydimethylsiloxane microchannel featuring sidewall sharp-edge structures and bare channels, and a piezoelement transducer is attached to a thin glass slide. When an external acoustic field is applied to the microchannel, the oscillation of the sharp-edge structures and the thin glass slide generate acoustic streaming flows which in turn rotate single cells and C. elegans in-plane and out-of-plane.

Original languageEnglish (US)
Pages (from-to)5120-5125
Number of pages6
JournalSmall (Weinheim an der Bergstrasse, Germany)
Volume12
Issue number37
DOIs
StatePublished - Oct 1 2016

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biomaterials
  • Chemistry(all)
  • Materials Science(all)

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