Acute Renal Failure following Immunoglobulin Therapy

Nasimul Ahsan, Laurel A. Wiegand, Catherine Abendroth, Eric C. Manning

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

Intravenous IgG infusion has infrequently been reported to cause acute renal failure. In almost all these reports, a sucrose containing IgG product was believed to be the cause of renal injury. Sucrose-induced osmotic nephrosis has been well described in the literature. In this report, we describe a case of acute anuric renal failure following a large infusion of intravenous IgG containing sucrose. Urine cytology demonstrated typical osmotic injury to the renal tubular epithelial cells. Early recovery of renal function was achieved by dialytic removal of sucrose from the circulation.

Original languageEnglish (US)
Pages (from-to)532-536
Number of pages5
JournalAmerican Journal of Nephrology
Volume16
Issue number6
DOIs
StatePublished - Jan 1 1996

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Passive Immunization
Acute Kidney Injury
Sucrose
Immunoglobulin G
Kidney
Intravenous Infusions
Nephrosis
Recovery of Function
Wounds and Injuries
Cell Biology
Epithelial Cells
Urine

All Science Journal Classification (ASJC) codes

  • Nephrology

Cite this

Ahsan, Nasimul ; Wiegand, Laurel A. ; Abendroth, Catherine ; Manning, Eric C. / Acute Renal Failure following Immunoglobulin Therapy. In: American Journal of Nephrology. 1996 ; Vol. 16, No. 6. pp. 532-536.
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Acute Renal Failure following Immunoglobulin Therapy. / Ahsan, Nasimul; Wiegand, Laurel A.; Abendroth, Catherine; Manning, Eric C.

In: American Journal of Nephrology, Vol. 16, No. 6, 01.01.1996, p. 532-536.

Research output: Contribution to journalArticle

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