Adequate margins for anorectal cancer can be achieved by single-site laparoscopy

David Stewart, Evangelos Messaris

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Introduction: To assess both the adequacy of surgical resection and the short-term postoperative outcomes for patients undergoing single-site laparoscopy (SSL) surgery involving low anterior resection (LAR) and abdominoperineal resection (APR) for malignancies. Subjects and Methods: Consecutive rectal and anal cancer patients who underwent SSL LAR and APR were studied. Use of neoadjuvant therapy, operative details, and 30-day complications were sought. Radial and distal margins of resection and the pathologist's evaluation of the mesorectum were analyzed. Results: Twelve patients (median age, 66 years) were identified; 11 (91%) were diagnosed with rectal adenocarcinoma and 1 (9%) with anal melanoma. Median location of the cancers was 5 cm from the anal verge, with 6 (55%) patients receiving neoadjuvant chemoradiation. Seven (58%) patients underwent an LAR, 2 of whom were also given a diverting ileostomy at surgery. Median body mass index was 28 kg/m 2 (range, 24-36 kg/m2). All resection margins were clear of tumor by histology, with the majority of patients having T3 (41%), N0 (58%) cancers. Median node yield was 18 nodes. The median distal margin was 3 cm, with a median radial margin of 6 mm. All specimens had an intact mesorectum. Conclusions: SSL resections for rectal and anal cancers can achieve adequate resection margins. Larger prospective studies are needed to validate oncologic outcomes for SSL.

Original languageEnglish (US)
Pages (from-to)316-322
Number of pages7
JournalJournal of Laparoendoscopic and Advanced Surgical Techniques
Volume23
Issue number4
DOIs
StatePublished - Apr 1 2013

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Laparoscopy
Anus Neoplasms
Neoplasms
Rectal Neoplasms
Ileostomy
Neoadjuvant Therapy
Melanoma
Histology
Adenocarcinoma
Body Mass Index
Prospective Studies
Margins of Excision

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

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title = "Adequate margins for anorectal cancer can be achieved by single-site laparoscopy",
abstract = "Introduction: To assess both the adequacy of surgical resection and the short-term postoperative outcomes for patients undergoing single-site laparoscopy (SSL) surgery involving low anterior resection (LAR) and abdominoperineal resection (APR) for malignancies. Subjects and Methods: Consecutive rectal and anal cancer patients who underwent SSL LAR and APR were studied. Use of neoadjuvant therapy, operative details, and 30-day complications were sought. Radial and distal margins of resection and the pathologist's evaluation of the mesorectum were analyzed. Results: Twelve patients (median age, 66 years) were identified; 11 (91{\%}) were diagnosed with rectal adenocarcinoma and 1 (9{\%}) with anal melanoma. Median location of the cancers was 5 cm from the anal verge, with 6 (55{\%}) patients receiving neoadjuvant chemoradiation. Seven (58{\%}) patients underwent an LAR, 2 of whom were also given a diverting ileostomy at surgery. Median body mass index was 28 kg/m 2 (range, 24-36 kg/m2). All resection margins were clear of tumor by histology, with the majority of patients having T3 (41{\%}), N0 (58{\%}) cancers. Median node yield was 18 nodes. The median distal margin was 3 cm, with a median radial margin of 6 mm. All specimens had an intact mesorectum. Conclusions: SSL resections for rectal and anal cancers can achieve adequate resection margins. Larger prospective studies are needed to validate oncologic outcomes for SSL.",
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Adequate margins for anorectal cancer can be achieved by single-site laparoscopy. / Stewart, David; Messaris, Evangelos.

In: Journal of Laparoendoscopic and Advanced Surgical Techniques, Vol. 23, No. 4, 01.04.2013, p. 316-322.

Research output: Contribution to journalArticle

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