Adhesion formation: Intraperitoneal catheters in surgical practice

George C. Zografos, Kreon M. Simeonidis, Aikaterini S. Parasi, Evangelos Messaris, Evangelos E. Menenakos, Ismene A. Dontas, Kiriaki C. Marti, George A. Androulakis

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

To compare the adhesion formation, in a rat model, of commercially available materials used as intraperitoneal catheters in clinical practice, pieces of polyurethane, Teflon, silicone, and polyvinyl chloride (PVC) were placed intraperitoneally in 36 female Wistar rats randomly assigned into four groups. Adhesion development was quantitated according to Nair's classification system (NCS). According to NCS, polyurethane showed the least adhesion formation, while the highest scores were found in the PVC group. Comparing the thickness and the firmness of adhesions in the four groups, significant differences were found, with the polyurethane group developing none or filmy and mild adhesions. In contrast, almost all the rats in the Teflon group developed thick and dense adhesions. Thus, polyurethane caused the least adhesion formation among the four materials evaluated, and can be used more extensively for the construction of catheters for prolonged intraperitoneal use.

Original languageEnglish (US)
Pages (from-to)37-43
Number of pages7
JournalJournal of Investigative Surgery
Volume15
Issue number1
DOIs
StatePublished - Apr 15 2002

All Science Journal Classification (ASJC) codes

  • Surgery

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