Adolescent brain maturation and smoking: What we know and where we're headed

David M. Lydon, Stephen J. Wilson, Amanda Child, Charles F. Geier

Research output: Contribution to journalReview article

68 Scopus citations

Abstract

Smoking is a leading cause of mortality and morbidity worldwide. Smoking initiation often occurs during adolescence. This paper reviews and synthesizes adolescent development and nicotine dependence literatures to provide an account of adolescent smoking from onset to compulsive use. We extend neurobiological models of adolescent risk-taking, that focus on the interplay between incentive processing and cognitive control brain systems, through incorporating psychosocial and contextual factors specific to smoking, to suggest that adolescents are more vulnerable than adults to cigarette use generally, but that individual differences exist placing some adolescents at increased risk for smoking. Upon smoking, adolescents are more likely to continue smoking due to the increased positive effects induced by nicotine during this period. Continued use during adolescence, may be best understood as reflecting drug-related changes to neural systems underlying incentive processing and cognitive control, resulting in decision-making that is biased towards continued smoking. Persistent changes following nicotine exposure that may underlie continued dependence are described. We highlight ways that interventions may benefit from a consideration of cognitive-neuroscience findings.

Original languageEnglish (US)
Pages (from-to)323-342
Number of pages20
JournalNeuroscience and Biobehavioral Reviews
Volume45
DOIs
StatePublished - Sep 2014

All Science Journal Classification (ASJC) codes

  • Neuropsychology and Physiological Psychology
  • Cognitive Neuroscience
  • Behavioral Neuroscience

Fingerprint Dive into the research topics of 'Adolescent brain maturation and smoking: What we know and where we're headed'. Together they form a unique fingerprint.

  • Cite this