AFM investigation of molecular level events at biomaterial-biological interface

Aashiish Agnihotri, Christopher Siedlecki

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Interaction of water and proteins with biomaterials constitutes the first events occurring at the biomaterial/biological interface, and these events are believed to guide further responses. In this study we report two aspects of these initial events as studied by atomic force microscopy (AFM). First the time dependent conformational changes in fibrinogen adsorbed on a model hydrophobic biomaterial (graphite) and second, the morphological changes in poly(urethane urea) associated with hydration.

Original languageEnglish (US)
Title of host publicationBioengineering, Proceedings of the Northeast Conference
EditorsK Moxon, D E Sherif, S Kanakasabai
Pages125-126
Number of pages2
StatePublished - 2002
EventIEEE 28th Annual Northeast Bioengineering Conference - Philadelphia, PA, United States
Duration: Apr 20 2002Apr 21 2002

Other

OtherIEEE 28th Annual Northeast Bioengineering Conference
CountryUnited States
CityPhiladelphia, PA
Period4/20/024/21/02

Fingerprint

Biocompatible Materials
Biomaterials
Atomic force microscopy
Graphite
Urethane
Urea
Hydration
Fibrinogen
Proteins
Water

All Science Journal Classification (ASJC) codes

  • Chemical Engineering(all)

Cite this

Agnihotri, A., & Siedlecki, C. (2002). AFM investigation of molecular level events at biomaterial-biological interface. In K. Moxon, D. E. Sherif, & S. Kanakasabai (Eds.), Bioengineering, Proceedings of the Northeast Conference (pp. 125-126)
Agnihotri, Aashiish ; Siedlecki, Christopher. / AFM investigation of molecular level events at biomaterial-biological interface. Bioengineering, Proceedings of the Northeast Conference. editor / K Moxon ; D E Sherif ; S Kanakasabai. 2002. pp. 125-126
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Agnihotri, A & Siedlecki, C 2002, AFM investigation of molecular level events at biomaterial-biological interface. in K Moxon, DE Sherif & S Kanakasabai (eds), Bioengineering, Proceedings of the Northeast Conference. pp. 125-126, IEEE 28th Annual Northeast Bioengineering Conference, Philadelphia, PA, United States, 4/20/02.

AFM investigation of molecular level events at biomaterial-biological interface. / Agnihotri, Aashiish; Siedlecki, Christopher.

Bioengineering, Proceedings of the Northeast Conference. ed. / K Moxon; D E Sherif; S Kanakasabai. 2002. p. 125-126.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Agnihotri A, Siedlecki C. AFM investigation of molecular level events at biomaterial-biological interface. In Moxon K, Sherif DE, Kanakasabai S, editors, Bioengineering, Proceedings of the Northeast Conference. 2002. p. 125-126