Age alters regional distribution of blood flow during moderate-intensity exercise

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

During dynamic exercise in warm environments, requisite increases in skin and active muscle blood flows are supported by increasing cardiac output (Q̇(c)) and redistributing flew away from splanchnic and renal circulations. To examine the effect of age on these responses, six young (Y; 26 ± 2 yr) and six older (O; 64 ± 2 yr) men performed upright cycle exercise at 35 and 60% of peak O2 consumption (V̇O(2 peak)) in 22 and 36°C environments. To further isolate age, the two age groups were closely matched for V̇O(2 peak), weight, surface area, and body composition. Measurements included heart rate, Q̇(c) (CO2 rebreathing), skin blood flow (from increases in forearm blood flow (venous occlusion plethysmography), splanchnic blood flow/indocyanine green dilution), renal blood flow (p-amino-hippurate clearance), and plasma norepinephrine concentration. There were no significant age differences in Q̇(c); however, in both environments the O group maintained Q̇(c) at a higher stroke volume and lower heart rate. At 60% V̇O(2 peak), forearm blood flow was significantly lower in the O subjects in each environment. Splanchnic blood flow fell (by 12-14% in both groups) at the lower intensity, then decreased to a greater extent at 60% V̇O(2 peak) in Y than in O subjects (e.g., -45 ± 2 vs. -33 ± 3% for the hot environment, P < 0.01). Renal blood flow was lower at rest in the O group, remained relatively constant at 35% V̇O(2 peak), then decreased by 20-25% in both groups at 60% V̇O(2 peak). At 60% V̇O(2 peak), 27 and 37% more total blood flow was redistributed away from these two circulations in the Y than in the O group at 22 and 36°, respectively. It was concluded that the greater increase in skin blood flow in Y subjects is partially supported by a greater redistribution of blood flow away from splanchnic and renal vascular beds.

Original languageEnglish (US)
Pages (from-to)1112-1119
Number of pages8
JournalJournal of Applied Physiology
Volume79
Issue number4
DOIs
StatePublished - Jan 1 1995

Fingerprint

Regional Blood Flow
Exercise
Viscera
Renal Circulation
Forearm
Skin
Heart Rate
Splanchnic Circulation
Indocyanine Green
Plethysmography
Body Composition
Cardiac Output
Stroke Volume
Blood Vessels
Norepinephrine
Age Groups
Kidney
Weights and Measures
Muscles

All Science Journal Classification (ASJC) codes

  • Physiology
  • Physiology (medical)

Cite this

@article{cac05be9fd3840de9ea5d0a1e2e6abd1,
title = "Age alters regional distribution of blood flow during moderate-intensity exercise",
abstract = "During dynamic exercise in warm environments, requisite increases in skin and active muscle blood flows are supported by increasing cardiac output (Q̇(c)) and redistributing flew away from splanchnic and renal circulations. To examine the effect of age on these responses, six young (Y; 26 ± 2 yr) and six older (O; 64 ± 2 yr) men performed upright cycle exercise at 35 and 60{\%} of peak O2 consumption (V̇O(2 peak)) in 22 and 36°C environments. To further isolate age, the two age groups were closely matched for V̇O(2 peak), weight, surface area, and body composition. Measurements included heart rate, Q̇(c) (CO2 rebreathing), skin blood flow (from increases in forearm blood flow (venous occlusion plethysmography), splanchnic blood flow/indocyanine green dilution), renal blood flow (p-amino-hippurate clearance), and plasma norepinephrine concentration. There were no significant age differences in Q̇(c); however, in both environments the O group maintained Q̇(c) at a higher stroke volume and lower heart rate. At 60{\%} V̇O(2 peak), forearm blood flow was significantly lower in the O subjects in each environment. Splanchnic blood flow fell (by 12-14{\%} in both groups) at the lower intensity, then decreased to a greater extent at 60{\%} V̇O(2 peak) in Y than in O subjects (e.g., -45 ± 2 vs. -33 ± 3{\%} for the hot environment, P < 0.01). Renal blood flow was lower at rest in the O group, remained relatively constant at 35{\%} V̇O(2 peak), then decreased by 20-25{\%} in both groups at 60{\%} V̇O(2 peak). At 60{\%} V̇O(2 peak), 27 and 37{\%} more total blood flow was redistributed away from these two circulations in the Y than in the O group at 22 and 36°, respectively. It was concluded that the greater increase in skin blood flow in Y subjects is partially supported by a greater redistribution of blood flow away from splanchnic and renal vascular beds.",
author = "{Kenney, Jr.}, {William Lawrence} and Ho, {C. W.}",
year = "1995",
month = "1",
day = "1",
doi = "10.1152/jappl.1995.79.4.1112",
language = "English (US)",
volume = "79",
pages = "1112--1119",
journal = "Journal of Applied Physiology",
issn = "8750-7587",
publisher = "American Physiological Society",
number = "4",

}

Age alters regional distribution of blood flow during moderate-intensity exercise. / Kenney, Jr., William Lawrence; Ho, C. W.

In: Journal of Applied Physiology, Vol. 79, No. 4, 01.01.1995, p. 1112-1119.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Age alters regional distribution of blood flow during moderate-intensity exercise

AU - Kenney, Jr., William Lawrence

AU - Ho, C. W.

PY - 1995/1/1

Y1 - 1995/1/1

N2 - During dynamic exercise in warm environments, requisite increases in skin and active muscle blood flows are supported by increasing cardiac output (Q̇(c)) and redistributing flew away from splanchnic and renal circulations. To examine the effect of age on these responses, six young (Y; 26 ± 2 yr) and six older (O; 64 ± 2 yr) men performed upright cycle exercise at 35 and 60% of peak O2 consumption (V̇O(2 peak)) in 22 and 36°C environments. To further isolate age, the two age groups were closely matched for V̇O(2 peak), weight, surface area, and body composition. Measurements included heart rate, Q̇(c) (CO2 rebreathing), skin blood flow (from increases in forearm blood flow (venous occlusion plethysmography), splanchnic blood flow/indocyanine green dilution), renal blood flow (p-amino-hippurate clearance), and plasma norepinephrine concentration. There were no significant age differences in Q̇(c); however, in both environments the O group maintained Q̇(c) at a higher stroke volume and lower heart rate. At 60% V̇O(2 peak), forearm blood flow was significantly lower in the O subjects in each environment. Splanchnic blood flow fell (by 12-14% in both groups) at the lower intensity, then decreased to a greater extent at 60% V̇O(2 peak) in Y than in O subjects (e.g., -45 ± 2 vs. -33 ± 3% for the hot environment, P < 0.01). Renal blood flow was lower at rest in the O group, remained relatively constant at 35% V̇O(2 peak), then decreased by 20-25% in both groups at 60% V̇O(2 peak). At 60% V̇O(2 peak), 27 and 37% more total blood flow was redistributed away from these two circulations in the Y than in the O group at 22 and 36°, respectively. It was concluded that the greater increase in skin blood flow in Y subjects is partially supported by a greater redistribution of blood flow away from splanchnic and renal vascular beds.

AB - During dynamic exercise in warm environments, requisite increases in skin and active muscle blood flows are supported by increasing cardiac output (Q̇(c)) and redistributing flew away from splanchnic and renal circulations. To examine the effect of age on these responses, six young (Y; 26 ± 2 yr) and six older (O; 64 ± 2 yr) men performed upright cycle exercise at 35 and 60% of peak O2 consumption (V̇O(2 peak)) in 22 and 36°C environments. To further isolate age, the two age groups were closely matched for V̇O(2 peak), weight, surface area, and body composition. Measurements included heart rate, Q̇(c) (CO2 rebreathing), skin blood flow (from increases in forearm blood flow (venous occlusion plethysmography), splanchnic blood flow/indocyanine green dilution), renal blood flow (p-amino-hippurate clearance), and plasma norepinephrine concentration. There were no significant age differences in Q̇(c); however, in both environments the O group maintained Q̇(c) at a higher stroke volume and lower heart rate. At 60% V̇O(2 peak), forearm blood flow was significantly lower in the O subjects in each environment. Splanchnic blood flow fell (by 12-14% in both groups) at the lower intensity, then decreased to a greater extent at 60% V̇O(2 peak) in Y than in O subjects (e.g., -45 ± 2 vs. -33 ± 3% for the hot environment, P < 0.01). Renal blood flow was lower at rest in the O group, remained relatively constant at 35% V̇O(2 peak), then decreased by 20-25% in both groups at 60% V̇O(2 peak). At 60% V̇O(2 peak), 27 and 37% more total blood flow was redistributed away from these two circulations in the Y than in the O group at 22 and 36°, respectively. It was concluded that the greater increase in skin blood flow in Y subjects is partially supported by a greater redistribution of blood flow away from splanchnic and renal vascular beds.

UR - http://www.scopus.com/inward/record.url?scp=0028856346&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028856346&partnerID=8YFLogxK

U2 - 10.1152/jappl.1995.79.4.1112

DO - 10.1152/jappl.1995.79.4.1112

M3 - Article

VL - 79

SP - 1112

EP - 1119

JO - Journal of Applied Physiology

JF - Journal of Applied Physiology

SN - 8750-7587

IS - 4

ER -