Aggressive bladder carcinoma in an HIV-positive man with tetraplegia and neurogenic bladder

Justin O. Benabdallah, Clinton W. Collins, Laura R. Carucci, Kenneth E. Moores, David R. Gater, Adam P. Klausner

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background/objective: Patients with neurogenic bladder secondary to spinal cord injury who are managed long term with an indwelling catheter are known to be at increased risk for transitional cell carcinoma of the bladder. Immunosuppression is a known risk factor for malignancies that often are more aggressive than those seen in normal populations. Method: Case report and discussion of management recommendations. Results: We summarize the case of a 44-year-old HIV-positive C5-C6 incomplete tetraplegic male (date of injury 1980), who was diagnosed with transitional cell carcinoma of the bladder and succumbed to disease within 6 months of diagnosis. The patient was a non-smoker who was never managed with an indwelling catheter. There has been no such case reported in the literature. Conclusions: HIV infection in the presence of a neurogenic bladder may carry an increased risk of aggressive bladder malignancy. More studies are warranted to determine whether routine annual screening with cystoscopy in all patients with HIV and neurogenic bladder is indicated.

Original languageEnglish (US)
Pages (from-to)248-250
Number of pages3
JournalJournal of Spinal Cord Medicine
Volume34
Issue number2
DOIs
StatePublished - Mar 1 2011

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Neurogenic Urinary Bladder
Quadriplegia
Urinary Bladder
Indwelling Catheters
Transitional Cell Carcinoma
HIV
Carcinoma
Cystoscopy
Spinal Cord Injuries
Immunosuppression
HIV Infections
Neoplasms
Wounds and Injuries
Population

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

Benabdallah, J. O., Collins, C. W., Carucci, L. R., Moores, K. E., Gater, D. R., & Klausner, A. P. (2011). Aggressive bladder carcinoma in an HIV-positive man with tetraplegia and neurogenic bladder. Journal of Spinal Cord Medicine, 34(2), 248-250. https://doi.org/10.1179/107902610X12883422813705
Benabdallah, Justin O. ; Collins, Clinton W. ; Carucci, Laura R. ; Moores, Kenneth E. ; Gater, David R. ; Klausner, Adam P. / Aggressive bladder carcinoma in an HIV-positive man with tetraplegia and neurogenic bladder. In: Journal of Spinal Cord Medicine. 2011 ; Vol. 34, No. 2. pp. 248-250.
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Benabdallah, JO, Collins, CW, Carucci, LR, Moores, KE, Gater, DR & Klausner, AP 2011, 'Aggressive bladder carcinoma in an HIV-positive man with tetraplegia and neurogenic bladder', Journal of Spinal Cord Medicine, vol. 34, no. 2, pp. 248-250. https://doi.org/10.1179/107902610X12883422813705

Aggressive bladder carcinoma in an HIV-positive man with tetraplegia and neurogenic bladder. / Benabdallah, Justin O.; Collins, Clinton W.; Carucci, Laura R.; Moores, Kenneth E.; Gater, David R.; Klausner, Adam P.

In: Journal of Spinal Cord Medicine, Vol. 34, No. 2, 01.03.2011, p. 248-250.

Research output: Contribution to journalArticle

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