Aging and the wandering brain: Age-related differences in the neural correlates of stimulus-independent thoughts

David Maillet, Roger E. Beaty, Areeba Adnan, Kieran C.R. Fox, Gary R. Turner, R. Nathan Spreng

Research output: Contribution to journalArticle

Abstract

In recent years, several studies have indicated that healthy older adults exhibit a reduction in task-unrelated thoughts compared to young adults. However, much less is known regarding age-related differences in time spent engaging in stimulus-independent thoughts or in their neural correlates in the absence of an ongoing task. In the current study, we collected functional magnetic resonance imaging (fMRI) data while 29 young (mean age = 22y) and 22 older (mean age = 70y) adults underwent experience sampling in the absence of an ongoing task (i.e., at "rest"). Although both age groups reported spending a similar amount of time engaged in stimulus-independent thoughts, older adults rated their thoughts as more present-oriented (rather than atemporal) and more novel. Moreover, controlling for these age-related differences in content, we found that experiencing stimulus-independent thoughts was associated with increased posterior cingulate and left angular gyrus activation across age groups compared to exhibiting an external focus of attention. When experiencing stimulus-independent thoughts, younger adults engaged medial and left lateral prefrontal cortex as well as left superior temporal gyrus to a greater degree than older adults. Taken together, our results suggest that, in the absence of an ongoing task, although young and older adults spend a similar amount of time engaging in stimulus-independent thoughts, the content and neural correlates of these thoughts differ with age.

Original languageEnglish (US)
Article numbere0223981
JournalPloS one
Volume14
Issue number10
DOIs
StatePublished - Jan 1 2019

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Young Adult
Brain
Aging of materials
Chemical activation
Sampling
brain
Age Groups
young adults
Parietal Lobe
Gyrus Cinguli
Temporal Lobe
Prefrontal Cortex
Magnetic Resonance Imaging
magnetic resonance imaging
Ecological Momentary Assessment
sampling

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • General

Cite this

Maillet, David ; Beaty, Roger E. ; Adnan, Areeba ; Fox, Kieran C.R. ; Turner, Gary R. ; Spreng, R. Nathan. / Aging and the wandering brain : Age-related differences in the neural correlates of stimulus-independent thoughts. In: PloS one. 2019 ; Vol. 14, No. 10.
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Aging and the wandering brain : Age-related differences in the neural correlates of stimulus-independent thoughts. / Maillet, David; Beaty, Roger E.; Adnan, Areeba; Fox, Kieran C.R.; Turner, Gary R.; Spreng, R. Nathan.

In: PloS one, Vol. 14, No. 10, e0223981, 01.01.2019.

Research output: Contribution to journalArticle

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