Allergic asthma

Thomas L. Mertz, Timothy J. Craig

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Allergic asthma, also known as atopic asthma, is one type of extrinsic asthma that is characterized by an exaggerated immune response to a variety of indoor and outdoor allergens. The most commonly associated indoor allergens are house dust mites, cockroaches, and animals such as cats. However, outdoor -allergens such as alternaria mold, ragweed, tree, and grass pollen are also known triggers. The relationship between asthma and allergy is very complex, and atopic individuals- seem to be at increased risk for asthma [1]. The clinical presentation of asthma can vary greatly and depends on the stage and severity of the underlying disease -process. The development of allergic asthma is dependent on the T-Helper two (TH2) -predominant immune response. The diagnosis of allergic asthma must be made clinically with consistent history and observed worsening of the condition following- exposure to a suspected allergen. Diagnostic testing, in general, is often not needed to make the diagnosis if the history is compelling. Pulmonary function testing (PFT) reveals the classic obstructive pattern of asthma with observed reversibility following administration of beta2 agonists. Specific sensitivity to suspected allergens can be ascertained by interpretation of skin prick testing or serum specific IgE levels. Treatment involves removing, if possible, the inciting allergens. Other treatments involve ones typically utilized in any asthmatic such as inhaled corticosteroids and beta2 agonists. In some patients airway remodeling can occur if the inflammatory response is left unchecked; therefore, controlling the underlying inflammation is imperative.

Original languageEnglish (US)
Title of host publicationChallenging Cases in Pulmonology
PublisherSpringer New York
Pages3-17
Number of pages15
ISBN (Electronic)9781441970985
ISBN (Print)1441970975, 9781441970978
DOIs
StatePublished - Nov 1 2013

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Asthma
Allergens
History
Dermatophagoides Antigens
Airway Remodeling
Ambrosia
Alternaria
Cockroaches
Pollen
Poaceae
Immunoglobulin E
Adrenal Cortex Hormones
Hypersensitivity
Cats
Fungi
Inflammation
Lung
Skin
Therapeutics
Serum

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Mertz, T. L., & Craig, T. J. (2013). Allergic asthma. In Challenging Cases in Pulmonology (pp. 3-17). Springer New York. https://doi.org/10.1007/978-1-4419-7098-5_1
Mertz, Thomas L. ; Craig, Timothy J. / Allergic asthma. Challenging Cases in Pulmonology. Springer New York, 2013. pp. 3-17
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Mertz, TL & Craig, TJ 2013, Allergic asthma. in Challenging Cases in Pulmonology. Springer New York, pp. 3-17. https://doi.org/10.1007/978-1-4419-7098-5_1

Allergic asthma. / Mertz, Thomas L.; Craig, Timothy J.

Challenging Cases in Pulmonology. Springer New York, 2013. p. 3-17.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Mertz TL, Craig TJ. Allergic asthma. In Challenging Cases in Pulmonology. Springer New York. 2013. p. 3-17 https://doi.org/10.1007/978-1-4419-7098-5_1