Alteration of human endothelial cell morphology, growth and their interaction with monocytes mediated by adhesion molecules under cyclic strain

Jong Yun, J. M. Anderson, N. P. Ziats

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The effects of cyclic strain on human endothelial cells (CE) and their interaction with monocytes to determine a possible role of cyclic strain in regulation and/or modulation of endothelial cell properties are examined. A computer-driven Flexercell Strain Unit is used for cyclic strain application on human endothelial cells. Endothelial cells under cyclic strain and static conditions are fixed in 10% buffered formalin and stained with eosin and May-Grunwald/Giemsa. Monocytes are then added for 30 minutes under strain or static condition and dried in vacuum. Results show that EC morphology and growth are significantly altered in response to cyclic strain.

Original languageEnglish (US)
Title of host publicationTransactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium
Editors Anon
PublisherSoc for Biomaterials
Pages286
Number of pages1
Volume1
Publication statusPublished - 1996
EventProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) - Toronto, Can
Duration: May 29 1996Jun 2 1996

Other

OtherProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2)
CityToronto, Can
Period5/29/966/2/96

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All Science Journal Classification (ASJC) codes

  • Materials Science(all)

Cite this

Yun, J., Anderson, J. M., & Ziats, N. P. (1996). Alteration of human endothelial cell morphology, growth and their interaction with monocytes mediated by adhesion molecules under cyclic strain. In Anon (Ed.), Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium (Vol. 1, pp. 286). Soc for Biomaterials.