Altered mechanisms of thermoregulatory vasoconstriction in aged human skin

Caitlin S. Thompson-Torgerson, Lacy Marie Alexander, William Lawrence Kenney, Jr.

Research output: Contribution to journalReview article

24 Citations (Scopus)

Abstract

Human exposure to cold stimulates cutaneous vasoconstriction by activating both sympathetic reflex and locally mediated pathways. Older humans are vulnerable to hypothermia because primary aging impairs thermoregulatory cutaneous vasoconstriction. This article highlights recent findings discussing how age-related decrements in sympathetic neurotransmission contribute directly to thermoregulatory impairment, whereas changes in local cold-induced intracellular signaling suggest a more generalized age-associated vascular dysfunction.

Original languageEnglish (US)
Pages (from-to)122-127
Number of pages6
JournalExercise and Sport Sciences Reviews
Volume36
Issue number3
DOIs
StatePublished - Jul 1 2008

Fingerprint

Vasoconstriction
Skin
Hypothermia
Synaptic Transmission
Blood Vessels
Reflex

All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

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Altered mechanisms of thermoregulatory vasoconstriction in aged human skin. / Thompson-Torgerson, Caitlin S.; Alexander, Lacy Marie; Kenney, Jr., William Lawrence.

In: Exercise and Sport Sciences Reviews, Vol. 36, No. 3, 01.07.2008, p. 122-127.

Research output: Contribution to journalReview article

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