Abstract
Human exposure to cold stimulates cutaneous vasoconstriction by activating both sympathetic reflex and locally mediated pathways. Older humans are vulnerable to hypothermia because primary aging impairs thermoregulatory cutaneous vasoconstriction. This article highlights recent findings discussing how age-related decrements in sympathetic neurotransmission contribute directly to thermoregulatory impairment, whereas changes in local cold-induced intracellular signaling suggest a more generalized age-associated vascular dysfunction.
Original language | English (US) |
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Pages (from-to) | 122-127 |
Number of pages | 6 |
Journal | Exercise and Sport Sciences Reviews |
Volume | 36 |
Issue number | 3 |
DOIs | |
State | Published - Jul 2008 |
All Science Journal Classification (ASJC) codes
- Orthopedics and Sports Medicine
- Physical Therapy, Sports Therapy and Rehabilitation